Abo Bibliothek: Guest
Digitales Portal Digitale Bibliothek eBooks Zeitschriften Referenzen und Berichte Forschungssammlungen
International Journal of Medicinal Mushrooms
Impact-faktor: 1.423 5-jähriger Impact-Faktor: 1.525 SJR: 0.431 SNIP: 0.716 CiteScore™: 2.6

ISSN Druckformat: 1521-9437
ISSN Online: 1940-4344

Volumes:
Volumen 22, 2020 Volumen 21, 2019 Volumen 20, 2018 Volumen 19, 2017 Volumen 18, 2016 Volumen 17, 2015 Volumen 16, 2014 Volumen 15, 2013 Volumen 14, 2012 Volumen 13, 2011 Volumen 12, 2010 Volumen 11, 2009 Volumen 10, 2008 Volumen 9, 2007 Volumen 8, 2006 Volumen 7, 2005 Volumen 6, 2004 Volumen 5, 2003 Volumen 4, 2002 Volumen 3, 2001 Volumen 2, 2000 Volumen 1, 1999

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushrooms.2017021239
pages 629-640

Anti-Inflammation and Lipogenic Inhibition of Taiwanofungus salmonea Mycelium and Grifola frondosa Fruiting Body

Rao-Chi Chien
Department of Food Science and Biotechnology, National Chung Hsing University, Taichung, Taiwan, R.O.C.; National Chung Hsing University/University of California Davis Plant and Food Biotechnology Center, National Chung Hsing University, Taichung, Taiwan, R.O.C.; Agricultural Biotechnology Center, National Chung Hsing University/University of California Davis Plant and Food Biotechnology Center, Taiwan, R.O.C.
Yi-Chi Yang
Department of Food Science and Biotechnology, National Chung Hsing University, Taichung, Taiwan, R.O.C.
Eric Icheng Lai
Department of Biotechnology, Hungkuang University, Taichung, Taiwan, R.O.C.
Jeng-Leun Mau
Department of Food Science and Biotechnology, National Chung-Hsing University, 145 Xingda Road, Taichung 40227, Taiwan, R.O.C.

ABSTRAKT

A long-term inflammatory response can cause the development of nonalcoholic steatohepatitis (NASH), which is mainly caused by abnormal metabolism of lipids in the liver. Taiwanofungus salmonea and Grifola frondosa, which are valuable medicinal mushrooms in Taiwan and exhibit many beneficial bioactivities, are used to evaluate effects on immune regulation in Raw 264.7 cells and on NASH-related responses in Hep G2 cells. According to the results, the production of proinflammatory cytokines was effectively decreased, whereas the production of interleukin-10 was increased. Lipid accumulation and reactive oxygen species production also declined, and free glycerol was released. The expression of acetyl-CoA carboxylase, fatty acid synthase, and sterol regulatory element-binding protein 1c was decreased. These results indicate that T. salmonea and G. frondosa are capable of reducing inflammatory responses and ameliorating NASH, indicating their potential as hepatoprotective dietary supplements.


Articles with similar content:

Anti-Inflammatory Activity of Biomass Extracts of the Bay Mushroom, Imleria badia (Agaricomycetes), in RAW 264.7 Cells
International Journal of Medicinal Mushrooms, Vol.18, 2016, issue 9
Joanna Gdula Argasinska, Agata Grzywacz, Wlodzimierz Opoka, Katarzyna Kala, Bozena Muszynska
Turmeric Bioprocessed with Mycelia from the Shiitake Culinary-Medicinal Mushroom Lentinus edodes (Agaricomycetes) Protects Mice Against Salmonellosis
International Journal of Medicinal Mushrooms, Vol.19, 2017, issue 4
Sung Phil Kim, Seok Hyun Nam, Mendel Friedman, Sang Jong Lee
The Agaricoglyceride of Royal Sun Medicinal Mushroom, Agaricus brasiliensis (Higher Basidiomycetes) is Anti-Inflammatory and Reverses Diabetic Glycemia in the Liver of Mice
International Journal of Medicinal Mushrooms, Vol.15, 2013, issue 4
Xu Gao, Yan Sun, Haitao Yu, Xiaodan Qi, Chunchao Han, Chun-Jing Zhang, Yan Shi
13-cis-Retinoic Acid Induces Apoptosis by Modulating Caspase-3, bcl-2, and p53 Gene Expression and Regulates the Activation of Transcription Factors in B16F-10 Melanoma Cells
Journal of Environmental Pathology, Toxicology and Oncology, Vol.27, 2008, issue 3
Chaluvally Raghavan Pradeep, Chandrasekharan Guruvayoorappan, Girija Kuttan
Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Polysaccharides Suppressed Adipogenesis and Stimulated Lipolysis in HPA-v and 3T3-L1 Adipocytes
International Journal of Medicinal Mushrooms, Vol.22, 2020, issue 9
Su Bu, Chunying Yuan, Hui Chen, Ximeng Zhu, Huihua Zheng, Chunhua Xu, Linguo Zhao, Zhenle Tian