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International Journal of Medicinal Mushrooms

Erscheint 12 Ausgaben pro Jahr

ISSN Druckformat: 1521-9437

ISSN Online: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

Indexed in

Ergosterol Peroxide and 9,11-Dehydroergosterol Peroxide from Ling Zhi or Reishi Medicinal Mushroom, Ganoderma lucidum (W. Curt.: Fr.) P. Karst. (Aphyllophoromycetideae) Mycelia Inhibit the Growth of Human Breast Adenocarcinoma MCF-7 Cells

Volumen 11, Ausgabe 3, 2009, pp. 249-257
DOI: 10.1615/IntJMedMushr.v11.i3.40
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ABSTRAKT

Two fungal steroids, namely, ergosterol peroxide (EP) and (9,11-dehydroergosterol peroxide (9(11)-DHEP), were isolated and identified from the mycelia of Ling Zhi or Reishi medicinal mushroom, Ganoderma lucidum, grown under submerged culture. Both EP and 9(11)-DHEP exhibited inhibitory effects on human breast adenocarcinoma MCF-7 cells. The nontumorigenic human breast MCF-10-2A cells were less susceptible to these two compounds. Flow cytometric analyses suggested that these two fungal steroids inhibited the growth of MCF-7 cells by inducing cell apoptosis.

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