Abo Bibliothek: Guest
Digitales Portal Digitale Bibliothek eBooks Zeitschriften Referenzen und Berichte Forschungssammlungen
International Journal of Medicinal Mushrooms
Impact-faktor: 1.423 5-jähriger Impact-Faktor: 1.525 SJR: 0.431 SNIP: 0.661 CiteScore™: 1.38

ISSN Druckformat: 1521-9437
ISSN Online: 1940-4344

Volumes:
Volumen 21, 2019 Volumen 20, 2018 Volumen 19, 2017 Volumen 18, 2016 Volumen 17, 2015 Volumen 16, 2014 Volumen 15, 2013 Volumen 14, 2012 Volumen 13, 2011 Volumen 12, 2010 Volumen 11, 2009 Volumen 10, 2008 Volumen 9, 2007 Volumen 8, 2006 Volumen 7, 2005 Volumen 6, 2004 Volumen 5, 2003 Volumen 4, 2002 Volumen 3, 2001 Volumen 2, 2000 Volumen 1, 1999

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushr.v14.i1.10
pages 1-20

New Scientific Approaches to Cancer Treatment: Can Medicinal Mushrooms Defeat the Curse of the Century?

Roumyana D. Petrova
Institute of Evolution, University of Haifa, Mount Carmel, Haifa; Migal-Galilee Technology Center, South Industrial Zone, Kiryat Shmona, Israel;Bulgarian Mycological Society, 23 Acad. G. Bonchev St., Sofia 1113, Bulgaria

ABSTRAKT

Modern science has spread so broadly and deeply within the nature of organisms that researchers have already established the molecular mechanisms of each vital process of human existence. Unfortunately, our age, heredity, lifestyle, race, and ethnicity are directly connected to the development and expression of many negative and even fatal processes, such as carcinogenesis. Many investigators have shown that the roots of carcinogenesis are hidden in the signaling pathways of cancer cells. Therefore, the pharmacological modulation of intracellular signal transduction pathways and the activation of transcription factors regulating gene expression represent a new and attractive therapeutic approach to cancer. It is already well established that medicinal mushrooms represent a potential source for biologically active compounds with immunomodulating, free radical scavenging, anti-inflammatory, antibacterial, antifungal, antiviral, hepatoprotective, antidiabetic, and anticancer activities. Moreover, low−molecular weight mushroom substances have been studied, and reported to interact with particular intracellular signaling pathways related to processes such as inflammation, cell differentiation and survival, apoptosis, angiogenesis, tumor progression and metastasis, etc. The present work compiles the available data on mushroom substances, in the form of extracts or chemically defined compounds, known to interfere with the above-mentioned essential processes related to the carcinogenesis and, thus, representing a new scientific approach to cancer treatment and prevention.


Articles with similar content:

Medicinal Mushrooms in Human Clinical Studies. Part I. Anticancer, Oncoimmunological, and Immunomodulatory Activities: A Review
International Journal of Medicinal Mushrooms, Vol.19, 2017, issue 4
Solomon P. Wasser
Medicinal Properties of Substances Occurring in Higher Basidiomycetes Mushrooms: Current Perspectives (Review)
International Journal of Medicinal Mushrooms, Vol.1, 1999, issue 1
Solomon P. Wasser, Alexander L. Weis
Medicinal Mushroom Science: History, Current Status, Future Trends, and Unsolved Problems
International Journal of Medicinal Mushrooms, Vol.12, 2010, issue 1
Solomon P. Wasser
Medicinal Mushrooms for Glycemic Control in Diabetes Mellitus: History, Current Status, Future Perspectives, and Unsolved Problems (Review)
International Journal of Medicinal Mushrooms, Vol.13, 2011, issue 5
Solomon P. Wasser, Hui-Chen Lo
Anticancer Activities of Medicinal Plants: Modulation of p53 Expression and Induction of Apoptosis
Critical Reviews™ in Eukaryotic Gene Expression, Vol.26, 2016, issue 3
Amna Parveen, Whang Wan Kyunn, Muhammad Sajid Hamid Akash, Kanwal Rehman