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ISSN Druckformat: 1521-9437
ISSN Online: 1940-4344
IF:
1.2
5-Year IF:
1.4
Immediacy Index:
0.3
Eigenfactor:
0.00066
JCI:
0.34
SJR:
0.274
SNIP:
0.41
CiteScore™::
2.8
H-Index:
37
Indexed in
The Artificial Cultivation of Medicinal Caterpillar Fungus, Ophiocordyceps sinensis (Ascomycetes): A Review
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ABSTRAKT
Caterpillar fungus, Ophiocordyceps sinensis (syn. Cordyceps sinensis), is highly valued in China as a dietary supplement or tonic food and natural remedy. The combination of the fungus and dead insect has been used as a traditional Chinese medicine for centuries, and evidence shows its efficacy on immunomodulatory potentials. The price of O. sinensis has continued to increase over the last few years due to growing worldwide demand, driving research to determine methods of artificial cultivation to make O. sinensis a more affordable material for commercial trade. This study highlights many aspects of artificial cultivation of O. sinensis, including separation of the anamorph, culture of the mycelium, cultivation of the fruiting bodies, bioecological characteristics of the host insect, and two patterns of artificial cultivation. In addition, this review discusses the current state, limitations, remedies, and future prospects, aiming to draw researchers' attention to the new frontier of research needs in this context.
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Tao Zui, Cao Li, Zhang Yi, Ye Yunshou, Han Richou, Laboratory Rearing ofThitarodes armoricanusandThitarodes jianchuanensis(Lepidoptera: Hepialidae), Hosts of the Chinese Medicinal FungusOphiocordyceps sinensis(Hypocreales: Ophiocordycipitaceae), Journal of Economic Entomology, 109, 1, 2016. Crossref
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Jin Jian, Zhong Can, Qin You, Cai Yuan, Zhen Lanping, Shen Bingbing, Chen Lin, Wan Dan, Qin Yuhui, Zhang Shuihan, A new cordycepin-producing caterpillar fungus Ophiocordyceps xuefengensis with artificial infection to the host, cultivation of mycelia and stromata, FEMS Microbiology Letters, 364, 20, 2017. Crossref
-
Zhang Ping, Li Saina, Li Juan, Wei Feng, Cheng Xianlong, Zhang Guifeng, Ma Shuangcheng, Liu Bin, Identification of Ophiocordyceps sinensis and Its Artificially Cultured Ophiocordyceps Mycelia by Ultra-Performance Liquid Chromatography/Orbitrap Fusion Mass Spectrometry and Chemometrics, Molecules, 23, 5, 2018. Crossref
-
Jin Jian, Zhou Rongrong, Xie Jing, Ye Huixuan, Liang Xuejuan, Zhong Can, Shen Bingbing, Qin You, Zhang Shuihan, Huang Luqi, Insights into Triterpene Acids in Fermented Mycelia of Edible Fungus Poria cocos by a Comparative Study, Molecules, 24, 7, 2019. Crossref
-
Cheong Peter Chiew Hing, Tan Chon Seng, Fung Shin Yee, Medicinal Mushrooms: Cultivation and Pharmaceutical Impact, in Biology of Macrofungi, 2018. Crossref
-
Jung Su-Jin, Jung Eun-Soo, Choi Eun-Kyung, Sin Hong-Sig, Ha Ki-Chan, Chae Soo-Wan, Immunomodulatory effects of a mycelium extract of Cordyceps (Paecilomyces hepiali; CBG-CS-2): a randomized and double-blind clinical trial, BMC Complementary and Alternative Medicine, 19, 1, 2019. Crossref
-
Jung Su Jin, Hwang Ji Hyun, Oh Mi Ra, Chae Soo Wan, Effects of Cordyceps militaris supplementation on the immune response and upper respiratory infection in healthy adults: a randomized, double-blind, placebo-controlled study, Journal of Nutrition and Health, 52, 3, 2019. Crossref
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Rao Zhongchen, Cao Li, Wu Hua, Qiu Xuehong, Liu Guiqing, Han Richou, Comparative Transcriptome Analysis of Thitarodes Armoricanus in Response to the Entomopathogenic Fungi Paecilomyces Hepiali and Ophiocordyceps Sinensis, Insects, 11, 1, 2019. Crossref
-
Turło Jadwiga, The biotechnology of higher fungi - current state and perspectives, Folia Biologica et Oecologica, 10, 2014. Crossref
-
Li Miaomiao, Meng Qian, Zhang Huan, Ni Ruoyao, Zhou Guiling, Zhao Yanni, Wu Peipei, Shu Ruihao, Qin Qilian, Zhang Jihong, Vegetative development and host immune interaction of Ophiocordyceps sinensis within the hemocoel of the ghost moth larva, Thitarodes xiaojinensis, Journal of Invertebrate Pathology, 170, 2020. Crossref
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Wu Hua, Rao Zhong-Chen, Cao Li, De Clercq Patrick, Han Ri-Chou, Infection of Ophiocordyceps sinensis Fungus Causes Dramatic Changes in the Microbiota of Its Thitarodes Host, Frontiers in Microbiology, 11, 2020. Crossref
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Wu Hua, Cao Li, He Meiyu, Han Richou, De Clercq Patrick, Interspecific Hybridization and Complete Mitochondrial Genome Analysis of Two Ghost Moth Species, Insects, 12, 11, 2021. Crossref
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Johri Srishti, Nair Yash Vignesh, Selvapandiyan A., Cultivation and Medicinal Uses of Cordyceps militaris (L.) Link: A Revolutionary Entomopathogenic Fungus, in Biology, Cultivation and Applications of Mushrooms, 2022. Crossref
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Zhong Can, Jin Jian, Zhou Rongrong, Liu Hao, Xie Jing, Wan Dan, Xiao Shengen, Zhang Shuihan, Comparative analysis of the complete mitochondrial genomes of four cordyceps fungi, Ecology and Evolution, 12, 4, 2022. Crossref
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Anyu Anawinla Ta, Zhang Wen-Hui, Xu Qi-He, Cultivated Cordyceps: A Tale of Two Treasured Mushrooms, Chinese Medicine and Culture, 4, 4, 2021. Crossref
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Tong Chaoqun, Wei Junhong, Pan Guoqing, Li Chunfeng, Zhou Zeyang, Study of Pathogenesis Using Fluorescent Strain of Cordyceps farinosa Revealed Infection of Thitarodes armoricanus Larvae via Digestive Tract, Insects, 13, 11, 2022. Crossref
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Shreedevasena S., Karthiba L., Raveena R., Ramyabharathi S. A., Salama Ehab A., Mohanraj J., Vanitha S., Anantha Raju P., Kamalakannan A., Jeyakumar P., Kichenaradjou M., Arunkumar P., Syamala M., Maheshwari P., Latha P., Murali Sankar P., Mass Production and Marketing of Compost Caterpillar Fungus Cordyceps sinensis, in Industrial Microbiology Based Entrepreneurship, 42, 2022. Crossref