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ISSN Druckformat: 2152-5102
ISSN Online: 2152-5110
Indexed in
Mass Transport Effects on Coronary Flow and Left Ventricular Mechanics
ABSTRAKT
The contractions of the left ventricle (LV) of the heart maintain the blood flow through the body's organs, including the coronary arteries which nourish the contracting and relaxing heart muscle. The effects of fluid and mass transport inside the muscle on the LV mechanics and coronary flow are demonstrated through the model simulation of the LV response to a step change in blood osmolality and the blockage of the lymphatic outflow. An integrated LV model, that takes into account the myocardial mechanics, the coronary flow, and the fluid and mass transport, is used in the analysis. The results show that fluid and mass transport have important effects on the myocardial mechanics and the coronary flow.