RT Journal Article ID 4ea707c95592e66d A1 Hodges, Kurt B. A1 Bachert, Emily A1 Cheng, Liang T1 Prostate Cancer Biomarkers: Current Status JF Critical Reviews™ in Oncogenesis JO CRO YR 2017 FD 2018-03-20 VO 22 IS 5-6 SP 253 OP 269 K1 prostate cancer K1 gene panel K1 RNA K1 DNA K1 proteomics K1 metabolomics K1 epigenetic signature AB Prostate cancer (PCa) is the second most frequently diagnosed cancer among men worldwide. Given the biological heterogeneity in localized PCa and its variable clinical course, a personalized approach to patient risk stratification and management is needed. A variety of high-throughput technologies, such as next-generation sequencing, transcriptomic, epigenetic, and metabolomic modalities have led to an improved understanding of the genomic basis of PCa and the identification of PCa biomarkers. Novel genomic approaches offer additional information to improve clinical decision making. The goal of this report is to review the use of currently available molecular biomarkers in the diagnosis and prognostication of PCa outcome. PB Begell House LK https://www.dl.begellhouse.com/journals/439f422d0783386a,5fec323e07ab6bc2,4ea707c95592e66d.html