RT Journal Article ID 57603a4b3ccc4b0b A1 Tsuk, Sharon A1 Lev, Yarden Har A1 Rotstein, Arie A1 Zeev, Aviva A1 Carasso, Refael A1 Steiner, Gilit T1 Effects of a Commercial Supplement of Ophiocordyceps sinensis and Ganoderma lucidum on Physiological Responses to Maximal Exercise in Healthy Young Participants JF International Journal of Medicinal Mushrooms JO IJM YR 2018 FD 2018-05-16 VO 20 IS 4 SP 359 OP 367 K1 Cordyceps sinensis K1 Ganoderma lucidum K1 medicinal mushrooms K1 Ophiocordyceps sinensis K1 physical fitness K1 Vo2max K1 Wingate test AB Cordyceps sinensis (=Ophiocordyceps sinensis) and Ganoderma lucidum are 2 medicinal mushrooms that have been suggested to have the potential to enhance exercise capacity. We used a commercial supplement combining a traditional Chinese medicine and G. lucidum and tested its effects on human physical, aerobic, and anaerobic capacities. Physical education students (n = 96; 43 women, 53 men; mean ± standard deviation age, 26.3 ± 3.21 years) were randomly divided into 3 groups: low-dose treatment, high-dose treatment, and placebo. Participants received the supplement or the placebo for 28-33 days. Both before and after the intervention, the participants performed a graded maximum oxygen consumption (Vo2max) test on a treadmill and a Wingate anaerobic cycle test (on a different day). The following parameters were measured and recorded during the maximal graded treadmill test: heart rate, oxygen consumption, respiratory exchange ratio, and ventilation. The following parameters were calculated from the Wingate anaerobic cycle test: maximal anaerobic power, mean anaerobic power, and fatigue index. The supplements did not affect Vo2max or the physiological responses upon maximal exercise during the graded treadmill test. In a similar way, they had no effect on peak or mean power, or fatigue index, as measured by the Wingate anaerobic test. A borderline interaction indicated a somewhat lower heart rate at rest after treatment; however, post hoc analysis did not reveal any further statistically significant differences (P = 0.047; F = 3.169). The findings indicate that dual supplementation with C. sinensis and G. lucidum had no effect on Vo2max, on physiological responses at peak exercise load during a graded maximal treadmill test, or on the parameters of anaerobic capacity. PB Begell House LK https://www.dl.begellhouse.com/journals/708ae68d64b17c52,31a39db86881b79c,57603a4b3ccc4b0b.html