RT Journal Article
ID 5ca3f2842ce68a95
A1 Moldavan, Mykhaylo 
A1 Grodzinskaya, Anna A.
A1 Wasser, Solomon P.
A1 Storozhuk, Victor M.
T1 Effects of Higher Basidiomycetes Mushrooms on the Hippocampal Slices in Rats
JF International Journal of Medicinal Mushrooms
JO IJM
YR 1999
FD 1999-04-28
VO 1
IS 2
SP 173
OP 180
K1 Higher Basidiomycetes
K1 extract
K1 pyramidal neurons
K1 hippocampal slice
K1 spike (impulse) activity
K1 rat.
AB Effects of water and ethanol extracts on spike activity of 28 neurons from the hippocampal stratum pyramidale (CA1 region) were studied in nine higher Basidiomycetes species: <i>Boletus edulis</i> (Bull.: Fr.), <i>Xerocomus badius</i> Fr., <i>Lentinus edodes</i> (Berk.) Sing., <i>Lactarius turpis</i> (Weinm.) Fr., <i>Amanita muscaria</i> (L.: Fr.) Hook., Stropharia aeruginosa (Curt.: Fr.) Quel., <i>Armillariella mellea</i> (Vahl.: Fr.) P. Karst, <i>Hypholoma fasciculare</i> (Huds.: Fr.) Kumm., and <i>Piptoporus betulinus</i> (Bull.: Fr.) P. Karst. <i>Lactarius turpis</i> and <i>Lentinus edodes</i> extracts caused the neuron excitation; <i>S. aeruginosa, H. fasciculare</i>, and <i>P. betulinus</i> extracts caused excitation or inhibition; <i>A. muscaria, B. edulis, X. badius</i>, and <i>A. mellea</i> clearly expressed inhibition responses. Extracts of <i>A. muscaria</i> rarely caused excitation or inhibition&minus;excitation responses. Whether the nature of the responses was inhibitory or excitatory was not associated with the extract concentration. Neuron responses occurred only with the application of extracts in the majority of the studied species. In some cases the neuron excitation was also manifest after the termination of application of extracts of <i>L. edodes, A. mellea, P. betulinus</i> (for 1&minus;5 min.) and especially <i>A. muscaria</i> when inhibition or excitation lasted for 6 to 12 min.
PB Begell House
LK https://www.dl.begellhouse.com/journals/708ae68d64b17c52,467a6b9619790c8f,5ca3f2842ce68a95.html