%0 Journal Article %A Ilhan-Sarac, Ozge %A Sekeroglu, Hande Taylan %A Sanac, Ali Sefik %A Ozyar, Enis %A Sener, Cumhur %D 2013 %I Begell House %K nasopharyngeal carcinoma, cranial nerve palsy, botulinum neurotoxin %N 3-4 %P 213-218 %R 10.1615/ForumImmunDisTher.2014008421 %T Use of Botulinum Neurotoxin in Cranial Nerve Paralysis due to Nasopharyngeal Carcinoma %U https://www.dl.begellhouse.com/journals/2c6306423483e001,40d53a501632f44a,6d39f0355badfefb.html %V 4 %X Nasopharyngeal carcinoma (NPC) is a malignant tumor of the nasopharynx arising from the epithelial cells. Extension of the primary tumor to the adjacent tissues can cause cranial nerve (CN) palsies. Although all CNs can be involved, the CN VI, CN V, CN VIII, CN IX, and CN XII are the most commonly affected. Isolated involvement frequently occurs in the CN V or CN VI. Nearly 70% of patients with CN palsy associated with NPC show improvement after radiotherapy. The recovery duration is generally within 6 months; therefore, botulinum neurotoxin injection should be considered for these patients to alleviate the complaints within this time period. %8 2014-05-06