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CHARACTERIZATION AND HIGH-THROUGHPUT MICROFLUIDIC APPLICATIONS OF AN OBSTRUCTED-CHANNEL FLOW CLASS

Kamen N. Beronov
Lehrstuhl für Strömungsmechanik, Universität Erlangen-Nürnberg Cauerstr. 4, D-91058 Erlangen, Germany

Nagihan Ozyilmaz
Lehrstuhl für Strömungsmechanik, Universität Erlangen-Nürnberg Cauerstr. 4, D-91058 Erlangen, Germany

Abstrakt

Microfluidic devices have been so far limited to creeping flow regimes, with various kinds of forcing, of mixing, of flow patterns, but with inadvertently low flow rates acceptable for miniaturized medical diagnostics but not for even small-batch synthesis. The latter and related applications began only very recently to attract industrial attention, bringing microfluidic design tools into difficulties as these are now confronted with chaotic and low-Reynolds-number turbulent flows. The present investigation focuses on a newly introduced, generic kind of mixing elements in microchannels and pressure driven flows in a Reynolds numbers range 500 < Re < 2000. It overcomes the mentioned limitations by resorting to direct 3D simulations and appropriate, highly efficient numerics. The results show clearly that turbulence can be generated, maintained at essentially linear cost, and controlled by suitable arrangements of large obstructions across the mean flow in micro channels. Genuine 3D turbulence can thus be maintained at Reynolds numbers several times lower than the critical Rec of straight channels.