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Journal of Environmental Pathology, Toxicology and Oncology
IF: 1.241 5-Year IF: 1.349 SJR: 0.356 SNIP: 0.613 CiteScore™: 1.61

ISSN Print: 0731-8898
ISSN Online: 2162-6537

Journal of Environmental Pathology, Toxicology and Oncology

DOI: 10.1615/JEnvironPatholToxicolOncol.v27.i1.60
pages 53-59

Increased Frequency of Chromosomal Aberrations in Industrial Painters Exposed to Lead-Based Paints

Dokku Madhavi
Department of Zoology, Osmania University, Hyderabad — 500 007, Andhra Pradesh, India
Kanapuram Rudrama Devi
Department of Zoology, Osmania University, Hyderabad — 500 007, Andhra Pradesh, India
Bammidi Lakshmi Sowjanya
Department of Zoology, Osmania University, Hyderabad — 500 007, Andhra Pradesh, India

ABSTRACT

The investigation was carried out in the peripheral lymphocytes of industrial painters who were exposed to dust and fumes of lead-based paints. Samples of peripheral blood were collected from 102 workers out of which 40 were smokers and 62 were nonsmokers. The painters in both the categories were divided in to 3 groups based on duration of exposure. Control data of 30 nonsmokers and 20 smokers belonging to the same socioeconomic group but not exposed to either radiation or toxic chemicals were studied. There was a significant increase in the frequency of chromosomal aberrations in the workers when compared to the controls. Further, smoking had an added effect on the frequency of aberrant metaphases.


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