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Critical Reviews™ in Immunology

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ISSN Print: 1040-8401

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The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.3 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.6 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00079 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.24 SJR: 0.429 SNIP: 0.287 CiteScore™:: 2.7 H-Index: 81

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Regulation of Airway Innate and Adaptive Immune Responses: The IL-17 Paradigm

Volume 28, Issue 4, 2008, pp. 269-279
DOI: 10.1615/CritRevImmunol.v28.i4.10
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Li-Yin Hung
Center for Comparative Respiratory Biology and Medicine, University of California, Davis, CA95616
Sharlene Velichko
Center for Comparative Respiratory Biology and Medicine, University of California, Davis, CA95616
Fei Huang
Center for Comparative Respiratory Biology and Medicine, University of California, Davis, CA95616
Philip Thai
Center for Comparative Respiratory Biology and Medicine, University of California, Davis, CA95616
Reen Wu
Center for Comparative Respiratory Biology and Medicine, University of California, USA

ABSTRACT

IL-17 is a proinflammatory cytokine produced by immune cells. Its significance in host defense and disease development has been demonstrated in various infection and autoimmune models. Recently, additional studies have shown that IL-17 is also important in modulating airway immune response in several aspects. Along with the well-established Th1/Th2 model, new discoveries regarding the Th17 lineage and IL-17 functions have added an extra twist to the already complicated cytokine network that regulates airway immunity. The IL-17 receptor is expressed on blood cells, as well as on structural cells such as the epithelial cells in the airway. Therefore, the effect of IL-17 on airway immunity is very broad, covering both the innate and the adaptive aspects. In this review, we summarize the findings of recent studies on IL-17 signaling and function in pulmonary immune response, and the implications of IL-17 in disease pathogenesis.

CITED BY

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  2. del Cacho Emilio, Gallego Margarita, Lillehoj Hyun, Quílez Joaquín, Lillehoj Erik P, Ramo Ana, Sánchez-Acedo Caridad, IL-17A regulates Eimeria tenella schizont maturation and migration in avian coccidiosis, Veterinary Research, 45, 1, 2014. Crossref

  3. Xu G., Zhang L., Wang D. Y., Xu R., Liu Z., Han D. M., Wang X. D., Zuo K. J., Li H. B., Opposing roles of IL-17A and IL-25 in the regulation of TSLP production in human nasal epithelial cells, Allergy, 65, 5, 2010. Crossref

  4. Montalbano Angela Marina, Riccobono Loredana, Siena Liboria, Chiappara Giuseppina, Di Sano Caterina, Anzalone Giulia, Gagliardo Rosalia, Ricciardolo Fabio L.M., Sorbello Valentina, Pipitone Loredana, Vitulo Patrizio, Profita Mirella, Cigarette smoke affects IL-17A, IL-17F and IL-17 receptor expression in the lung tissue: Ex vivo and in vitro studies, Cytokine, 76, 2, 2015. Crossref

  5. Martín Pilar, Gómez Manuel, Lamana Amalia, Marín Adela Matesanz, Cortés José R., Ramírez-Huesca Marta, Barreiro Olga, López-Romero Pedro, Gutiérrez-Vázquez Cristina, de la Fuente Hortensia, Cruz-Adalia Aránzazu, Sánchez-Madrid Francisco, The leukocyte activation antigen CD69 limits allergic asthma and skin contact hypersensitivity, Journal of Allergy and Clinical Immunology, 126, 2, 2010. Crossref

  6. Holt Patrick G., Strickland Deborah H., Interactions between innate and adaptive immunity in asthma pathogenesis: New perspectives from studies on acute exacerbations, Journal of Allergy and Clinical Immunology, 125, 5, 2010. Crossref

  7. Fahy John V., Dickey Burton F., Airway Mucus Function and Dysfunction, New England Journal of Medicine, 363, 23, 2010. Crossref

  8. Albano Giusy Daniela, Bonanno Anna, Cavalieri Luca, Ingrassia Eleonora, Di Sano Caterina, Siena Liboria, Riccobono Loredana, Gagliardo Rosalia, Profita Mirella, Effect of High, Medium, and Low Molecular Weight Hyaluronan on Inflammation and Oxidative Stress in anIn VitroModel of Human Nasal Epithelial Cells, Mediators of Inflammation, 2016, 2016. Crossref

  9. Albano Giusy Daniela, Di Sano Caterina, Bonanno Anna, Riccobono Loredana, Gagliardo Rosalia, Chanez Pascal, Gjomarkaj Mark, Montalbano Angela Marina, Anzalone Giulia, La Grutta Stefania, Ricciardolo Fabio Luigi Massimo, Profita Mirella, Tasken Kjetil, Th17 Immunity in Children with Allergic Asthma and Rhinitis: A Pharmacological Approach, PLoS ONE, 8, 4, 2013. Crossref

  10. Leach Richard J., O'Neill Ronan G., Fitzpatrick Julie L., Williams John L., Glass Elizabeth J., Varga Steven M., Quantitative Trait Loci Associated with the Immune Response to a Bovine Respiratory Syncytial Virus Vaccine, PLoS ONE, 7, 3, 2012. Crossref

  11. Anzalone Giulia, Gagliardo Rosalia, Bucchieri Fabio, Albano Giusy Daniela, Siena Liboria, Montalbano Angela Marina, Bonanno Anna, Riccobono Loredana, Pieper Michael Paul, Gjomarkaj Mark, Profita Mirella, IL-17A induces chromatin remodeling promoting IL-8 release in bronchial epithelial cells: Effect of Tiotropium, Life Sciences, 152, 2016. Crossref

  12. Montalbano Angela Marina, Albano Giusy Daniela, Bonanno Anna, Riccobono Loredana, Di Sano Caterina, Ferraro Maria, Siena Liboria, Anzalone Giulia, Gagliardo Rosalia, Pieper Michael Paul, Gjomarkaj Mark, Profita Mirella, Autocrine Acetylcholine, Induced by IL-17A via NFκB and ERK1/2 Pathway Activation, Promotes MUC5AC and IL-8 Synthesis in Bronchial Epithelial Cells, Mediators of Inflammation, 2016, 2016. Crossref

  13. Liu Zhan-Ju, Yadav Praveen K, Su Jing-Ling, Wang Jun-Shan, Fei Ke, Potential role of Th17 cells in the pathogenesis ofinflammatory bowel disease, World Journal of Gastroenterology, 15, 46, 2009. Crossref

  14. Mori Kazutaka, Fujisawa Tomoyuki, Kusagaya Hideki, Yamanaka Katsumasa, Hashimoto Dai, Enomoto Noriyuki, Inui Naoki, Nakamura Yutaro, Maekawa Masato, Suda Takafumi, Thatcher Thomas H, Synergistic Proinflammatory Responses by IL-17A and Toll-Like Receptor 3 in Human Airway Epithelial Cells, PLOS ONE, 10, 9, 2015. Crossref

  15. Yamanaka Katsumasa, Fujisawa Tomoyuki, Kusagaya Hideki, Mori Kazutaka, Niwa Mitsuru, Furuhashi Kazuki, Kono Masato, Hamada Etsuko, Suda Takafumi, Maekawa Masato, IL-13 regulates IL-17C expression by suppressing NF-κB-mediated transcriptional activation in airway epithelial cells, Biochemical and Biophysical Research Communications, 495, 1, 2018. Crossref

  16. Anzalone Giulia, Albano Giusy Daniela, Montalbano Angela Marina, Riccobono Loredana, Bonanno Anna, Gagliardo Rosalia, Bucchieri Fabio, Marchese Roberto, Moscato Monica, Profita Mirella, IL-17A-associated IKK-α signaling induced TSLP production in epithelial cells of COPD patients, Experimental & Molecular Medicine, 50, 10, 2018. Crossref

  17. Park Seoung Ju, Lee Kyung Sun, Kim So Ri, Min Kyung Hoon, Choe Yeong Hun, Moon Hee, Chae Han Jung, Yoo Wan Hee, Lee Yong Chul, Peroxisome Proliferator-Activated Receptor γ Agonist Down-Regulates IL-17 Expression in a Murine Model of Allergic Airway Inflammation, The Journal of Immunology, 183, 5, 2009. Crossref

  18. Wang Chuanwu, Kang Seung G., HogenEsch Harm, Love Paul E., Kim Chang H., Retinoic Acid Determines the Precise Tissue Tropism of Inflammatory Th17 Cells in the Intestine, The Journal of Immunology, 184, 10, 2010. Crossref

  19. Zhang Yuanfeng, Wang Zheyi, Zhang Yue, Tong Hongxuan, Zhang Yiling, Lu Tao, Potential Mechanisms for Traditional Chinese Medicine in Treating Airway Mucus Hypersecretion Associated With Coronavirus Disease 2019, Frontiers in Molecular Biosciences, 7, 2020. Crossref

  20. Parvez Faruque, Lauer Fredine T., Factor-Litvak Pam, Islam Tariqul, Eunus Mahbubul, Horayara M. Abu, Rahman Mizanour, Sarwar Golam, Ahsan Habibul, Graziano Joseph H., Burchiel Scott W., Hossain Khaled, Exposure to arsenic and level of Vitamin D influence the number of Th17 cells and production of IL-17A in human peripheral blood mononuclear cells in adults, PLOS ONE, 17, 4, 2022. Crossref

  21. Kusagaya Hideki, Fujisawa Tomoyuki, Yamanaka Katsumasa, Mori Kazutaka, Hashimoto Dai, Enomoto Noriyuki, Inui Naoki, Nakamura Yutaro, Wu Reen, Maekawa Masato, Suda Takafumi, Chida Kingo, Toll-Like Receptor–Mediated Airway IL-17C Enhances Epithelial Host Defense in an Autocrine/Paracrine Manner, American Journal of Respiratory Cell and Molecular Biology, 50, 1, 2014. Crossref

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