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Critical Reviews™ in Eukaryotic Gene Expression
IF: 2.156 5-Year IF: 2.255 SJR: 0.649 SNIP: 0.599 CiteScore™: 3

ISSN Print: 1045-4403
ISSN Online: 2162-6502

Critical Reviews™ in Eukaryotic Gene Expression

DOI: 10.1615/CritRevEukaryotGeneExpr.2018024574
pages 343-348

The Use of Scaffolds in Cartilage Regeneration

Rasime Kalkan
Near East University, Faculty of Medicine, Department of Medical Genetics, Cyprus
Chidi Wilson Nwekwo
Department of Biomedical Engineering, Faculty of Engineering, Near East University, Nicosia, North Cyprus, Turkey; Tissue Engineering and Biomaterials Research Center, Center of Excellence, Near East University, Cyprus
Terin Adali
Department of Biomedical Engineering, Faculty of Engineering, Near East University, Nicosia, North Cyprus, Turkey; Tissue Engineering and Biomaterials Research Center, Center of Excellence, Near East University, Cyprus

ABSTRACT

Scaffolds are important tools in tissue engineering and play a unique role in tissue regeneration and repair of damaged tissues. A variety of natural, synthetic, and composite scaffold types can be used in cartilage tissue engineering. The limited capability of cartilage to repair itself has always been a problem during recovery from damage. The success of cartilage regeneration is dependent on a couple of factors, but the basic properties of scaffolds are biocompatibility, degradability under physiological conditions, and structural support for cell attachment. In this review, we summarize the use of different scaffold types in cartilage regeneration.


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