Library Subscription: Guest
Begell Digital Portal Begell Digital Library eBooks Journals References & Proceedings Research Collections
Critical Reviews™ in Eukaryotic Gene Expression
IF: 2.156 5-Year IF: 2.255 SJR: 0.649 SNIP: 0.599 CiteScore™: 3

ISSN Print: 1045-4403
ISSN Online: 2162-6502

Critical Reviews™ in Eukaryotic Gene Expression

DOI: 10.1615/CritRevEukaryotGeneExpr.2018022771
pages 163-175

Nanotechnology: An Emerging Therapeutic Option for Breast Cancer

Zulfia Hussain
Institute of Pharmacy, Physiology and Pharmacology, University of Agriculture, Faisalabad-38040, Pakistan
Junaid Ali Khan
Institute of Pharmacy, Physiology and Pharmacology, University of Agriculture, Faisalabad-38040, Pakistan
Sehrish Murtaza
Institute of Pharmacy, Physiology and Pharmacology, University of Agriculture Faisalabad (UAF)-38040, Pakistan

ABSTRACT

The pharmacological application of nanodevices and systems is a rapidly emerging nanotechnology that is raising new possibilities in the diagnosis and therapy of different diseases. Nanotechnology has been providing promising tools for chemotherapy especially in cancer treatment. Nanotechnology deals with physical and biochemical properties of nanoparticles in the clinical application of drugs. Targeted nanoparticle drug delivery is intended to reduce the side effects of anticancer drugs with both decreases in consumption and treatment expenses, which are the major hurdles in conventional cancer treatment. The characteristic small size and special coating of nanoparticles facilitates the delivery of hydrophobic anticancer drugs to specific sites with reduced opsonization by defense mechanisms of the body. One of the vast applications of nanotechnology is the diagnosis, treatment, and prevention of breast cancers. Breast cancer is associated with high morbidity and mortality and is the second leading cause of death in Western countries. A large number of nanoparticles have been developed, specifically targeting metastasized tumors of the breast. The present review focuses on the application of different types of nanoparticles including gold, polymeric, and magnetic nanoparticles in the treatment of breast cancer.


Articles with similar content:

A REVIEW ON RECENT ADVANCEMENTS IN THE HEMODYNAMICS OF NANO-DRUG DELIVERY SYSTEMS
Nanoscience and Technology: An International Journal, Vol.11, 2020, issue 1
B. Vasu, O. Anwar Bég, P. V. S. N. Murthy, Ponnaiah Saikrishnan, Jayati Tripathi, Rama Subba Reddy Gorla, V. Ramachandra Prasad, Ankita Dubey
Recent Advances in Nanoparticle-Based Targeted Drug-Delivery Systems Against Cancer and Role of Tumor Microenvironment
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.34, 2017, issue 4
Usman Ali Ashfaq, Muhammad Zubair Yousaf, Erum Yasmeen, Muhammad Riaz
Current Nanotechnological Strategies for Treating Glaucoma
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.31, 2014, issue 5
Goutam Rath, Tarun Garg, Amit Kumar Goyal, Gagandeep Goyal
Exploiting the Tumor Phenotype Using Biodegradable Submicron Carriers of Chemotherapeutic Drugs
Critical Reviews™ in Oncogenesis, Vol.19, 2014, issue 3-4
Aliasger K. Salem, Sean M. Geary
Bioconjugates: Harnessing Potential for Effective Therapeutics
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.26, 2009, issue 2
Piush Khare, Nitin K. Jain, Aviral Jain, Vandana Soni, Arvind Gulbake, Sanjay Kumar Jain