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International Journal of Medicinal Mushrooms
IF: 1.423 5-Year IF: 1.525 SJR: 0.433 SNIP: 0.661 CiteScore™: 1.38

ISSN Print: 1521-9437
ISSN Online: 1940-4344

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushr.v14.i5.60
pages 481-490

Naturally Occurring Medicinal Mushroom-Derived Antimicrobials: A Case-Study Using Lingzhi or Reishi Ganoderma lucidum (W. Curt.:Fr.) P. Karst. (Higher Basidiomycetes)

Alka S. Karwa
Department of Biotechnology, Amravati University, Amravati 444602, India
Mahendra K. Rai
Department of Biotechnology, SGB Amravati University, Amravati, Maharashtra-444 602, India

ABSTRACT

Antibacterial activity of Lingzhi or Reishi medicinal mushroom, Ganoderma lucidum, collected from Central India was evaluated against four bacterial pathogens. Ethyl alcohol and water extracts of fruit body powder were tested using the disc diffusion method against Staphylococcus aureus, Klebsiella pneumoniae, Bacillus cereus, and Pseudomonas aeruginosa. It was noted that the aqueous extract inhibited growth of pathogenic bacteria. The combined effect of fruit body extract with synthetic antibiotic discs was found to increase the activity significantly more than the antibiotics alone. The present study is an attempt to assess antibacterial activity of extracts of G. lucidum singly and in combination. The combination of G. lucidum with commercial antibiotics proves that it enhances antibacterial activity.


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