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International Journal of Medicinal Mushrooms

Published 12 issues per year

ISSN Print: 1521-9437

ISSN Online: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

Indexed in

Antimicrobial Effect of the Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Higher Basidiomycetes) and Its Main Compounds

Volume 16, Issue 1, 2014, pp. 77-84
DOI: 10.1615/IntJMedMushr.v16.i1.70
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ABSTRACT

Mushrooms are considered one of the richest sources of natural antibiotics, and various species of them inhibit the growth of a wide diversity of microorganisms. Ganoderma lucidum, a well-known medicinal mushroom. has many pharmacological and biological activities including an antimicrobial effect, although few studies have investigated the antibacterial and antifungal effects of its purified compounds. The chemical structure of the purified compounds from the hexane fraction was elucidated as ergosta-7,22-dien-3β-yl acetate, ergosta-5,7,22-trien-3β-yl acetate (isopyrocalciferol acetate), ergosta-7,22-dien-3-one, ergosta-7,22-dien-3β-ol, and ergosta-5,7,22-trien-3β-ol (ergostrol). In addition, the structure of ganodermadiol was demonstrated after purification from the chloroform fraction. The fractions inhibited Gram-positive bacteria and yeast, with minimum inhibitory concentration values of 6.25 mg/mL, but were ineffective against Gram-negative bacteria in the tested concentrations. The results were comparable for isolated compounds, whereas the mixture of ergosta-7,22-dien-3β-yl acetate and isopyrocalciferol acetate was weakly effective against Escherichia coli (minimum inhibitory concentration, 10 mg/mL). It could be assumed that the antimicrobial effect of crude fractions is the consequence of mixing triterpenoid and steroid compounds.

CITED BY
  1. Leliebre-Lara Vivian, Monzote Fidalgo Lianet, Pferschy-Wenzig Eva-Maria, Kunert Olaf, Nogueiras Lima Clara, Bauer Rudolf, In Vitro Antileishmanial Activity of Sterols from Trametes versicolor (Bres. Rivarden), Molecules, 21, 8, 2016. Crossref

  2. Tang Siu W., Tang Wayne H., Leonard Brian E., Herbal medicine for psychiatric disorders: Psychopharmacology and neuroscience-based nomenclature, The World Journal of Biological Psychiatry, 20, 8, 2019. Crossref

  3. Yıldız Sibel, Yılmaz Ayşenur, Can Zehra, Tabbouche Sana Adal, Kılıç Ali Osman, Sesli Ertuğrul, SOME BIOACTIVE PROPERTIES OF WILD AND COMMERCIAL MUSHROOM SPECIES, Journal of Food and Health Science, 2017. Crossref

  4. Bhardwaj Anuja, Misra Kshipra, Ganoderma sp.: The Royal Mushroom for High-Altitude Ailments, in Management of High Altitude Pathophysiology, 2018. Crossref

  5. Rezaeian Sharareh, Pourianfar Hamid R., Differences in antibacterial effectiveness between the whole extract and high-performance liquid chromatography-separated constituents from the cultivated mushroom Agaricus bisporus, Journal of Food Measurement and Characterization, 12, 2, 2018. Crossref

  6. Chan Yow San, Chong Khim Phin , Antimicrobial Activity and Metabolite Analysis of Ganoderma boninense Fruiting Body, Journal of Pure and Applied Microbiology, 14, 2, 2020. Crossref

  7. El Sheikha Aly Farag El, Nutritional Profile and Health Benefits of Ganoderma lucidum “Lingzhi, Reishi, or Mannentake” as Functional Foods: Current Scenario and Future Perspectives, Foods, 11, 7, 2022. Crossref

  8. Xu Juan, Xiao CongMei, Xu HaiShun, Yang ShengXiang, Chen ZheMing, Wang HongZhen, Zheng BingSong, Mao BiZeng, Wu XueQian, Anti-inflammatory effects of Ganoderma lucidum sterols via attenuation of the p38 MAPK and NF-κB pathways in LPS-induced RAW 264.7 macrophages, Food and Chemical Toxicology, 150, 2021. Crossref

  9. Elisashvili Vladimir, Asatiani Mikheil D., Khardziani Tamar, Rai Mahendra, Natural Antimicrobials from Basidiomycota Mushrooms, in Promising Antimicrobials from Natural Products, 2022. Crossref

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