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International Journal of Medicinal Mushrooms

Published 12 issues per year

ISSN Print: 1521-9437

ISSN Online: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Hypolipidemic and Hepatic Steatosis Preventing Activities of the Wood Ear Medicinal Mushroom Auricularia auricula-judae (Higher Basidiomycetes) Ethanol Extract In Vivo and In Vitro

Volume 17, Issue 8, 2015, pp. 723-734
DOI: 10.1615/IntJMedMushrooms.v17.i8.30
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ABSTRACT

Obesity, a rapidly growing threat to human health worldwide, is responsible for a large proportion of the total burden of disease. Therefore, obesity control could be a vital scheme to prevent many diseases. The aim of this study was to examine the activities and mechanism of Auricularia auricula-judae 70% ethanol extract (AAE) in preventing hypolipidemic and hepatic steatosis. A normal diet (ND) and a high-fat diet (HFD) with or without 0.1% (w/w), 0.3% (w/w), and 1% (w/w) AAE were given to male C57BL/6 mice. Plasma lipids and liver enzymes were measured and tissue sections of liver were examined. Further mechanistic studies of mouse 3T3-L1 adipocytes were performed in vitro by verifying triglyceride, glycerol, and glycerol-3-phosphate dehydrogenase activity and messenger RNA expression of adipogenic and lipogenic genes using reverse transcriptase polymerase chain reaction amplification. Body weight and adipose tissue mass were significantly reduced in mice fed an ND and a HFD plus AAE compared with mice fed an HFD. In AAE-supplemented groups, plasma lipids and liver enzymes decreased dose-dependently. AAE suppressed the expression of adipogenic/lipogenic genes (PPARγ, C/EBPα, FAS) in 3T3-L1 cells without cytotoxicity. These findings suggest that AAE may reduce the risk of hepatic steatosis by modulating plasma lipids via the regulation of adipogenic/lipogenic transcriptional factors. AAE may have interesting applications to improve plasma lipids and liver enzymes.

CITED BY
  1. Zou Li, Sun Tingting, Yang Yuanyi, Zhang Linfang, Zhang Jian, Molecular characterization of a glycoside hydrolase family-51 α-L-arabinofuranosidase from Auricularia auricula, Biotechnology & Biotechnological Equipment, 31, 3, 2017. Crossref

  2. Bandara Asanka R., Karunarathna Samantha C., Mortimer Peter E., Hyde Kevin D., Khan Sehroon, Kakumyan Pattana, Xu Jianchu, First successful domestication and determination of nutritional and antioxidant properties of the red ear mushroom Auricularia thailandica (Auriculariales, Basidiomycota), Mycological Progress, 16, 11-12, 2017. Crossref

  3. Friedman Mendel, Mushroom Polysaccharides: Chemistry and Antiobesity, Antidiabetes, Anticancer, and Antibiotic Properties in Cells, Rodents, and Humans, Foods, 5, 4, 2016. Crossref

  4. Wu Zhichao, Zhang Min, Yang Huandong, Zhou Huabin, Yang Hailong, Production, physico-chemical characterization and antioxidant activity of natural melanin from submerged cultures of the mushroom Auricularia auricula, Food Bioscience, 26, 2018. Crossref

  5. Hossain Md. Akil, Lee Seung-Jin, Park Na-Hye, Birhanu Biruk Tesfaye, Mechesso Abraham Fikru, Park Ji-Yong, Park Eun-Jin, Lee Sam-Pin, Youn Sun-Joo, Park Seung-Chun, Enhancement of Lipid Metabolism and Hepatic Stability in Fat-Induced Obese Mice by Fermented Cucurbita moschata Extract, Evidence-Based Complementary and Alternative Medicine, 2018, 2018. Crossref

  6. Ganesan Kumar, Xu Baojun, Anti-Obesity Effects of Medicinal and Edible Mushrooms, Molecules, 23, 11, 2018. Crossref

  7. Zhao Shuang, Zhang Shuman, Zhang Weiwei, Gao Yi, Rong Chengbo, Wang Hexiang, Liu Yu, Wong Jack Ho, Ng Tzibun, First demonstration of protective effects of purified mushroom polysaccharide-peptides against fatty liver injury and the mechanisms involved, Scientific Reports, 9, 1, 2019. Crossref

  8. Wei Chunyan, Wang Jingjing, Duan Cuicui, Fan Huimei, Liu Xiaoxiao, Aqueous Extracts of Se-Enriched Auricularia auricular Exhibits Antioxidant Capacity and Attenuate Liver Damage in High-Fat Diet/Streptozotocin-Induced Diabetic Mice, Journal of Medicinal Food, 23, 2, 2020. Crossref

  9. BAO Yi-Hong, SUN Kai-Feng, GUO Yang, Effect of molecular weight on hypolipidemic and hypoglycemic activities of fermented Auriculaia auricula supernatant, Food Science and Technology, 40, suppl 1, 2020. Crossref

  10. Liu Enchao, Ji Yuan, Zhang Fang, Liu Bingjie, Meng Xianghong, Review on Auricularia auricula-judae as a Functional Food: Growth, Chemical Composition, and Biological Activities, Journal of Agricultural and Food Chemistry, 69, 6, 2021. Crossref

  11. Islam Tahidul, Ganesan Kumar, Xu Baojun, Insights into health-promoting effects of Jew's ear (Auricularia auricula-judae), Trends in Food Science & Technology, 114, 2021. Crossref

  12. Mustafa Faheem, Chopra Hitesh, Baig Atif Amin, Avula Satya Kumar, Kumari Sony, Mohanta Tapan Kumar, Saravanan Muthupandian, Mishra Awdhesh Kumar, Sharma Nanaocha, Mohanta Yugal Kishore, Edible Mushrooms as Novel Myco-Therapeutics: Effects on Lipid Level, Obesity and BMI, Journal of Fungi, 8, 2, 2022. Crossref

  13. Kour Harpreet, Kour Satwinder, Sharma Yashpal, Singh Shaveta, Sharma Isha, Kour Divjot, Yadav Ajar Nath, Bioprospecting of Industrially Important Mushrooms, in Industrially Important Fungi for Sustainable Development, 2021. Crossref

  14. Dinda Biswanath, Dinda Manikarna, Natural Products, a Potential Source of New Drugs Discovery to Combat Obesity and Diabetes: Their Efficacy and Multi-targets Actions in Treatment of These Diseases, in Natural Products in Obesity and Diabetes, 2022. Crossref

  15. Shi Silin, Li Kailin, Peng Jie, Li Jian, Luo Lilan, Liu Mingjuan, Chen Yuqi, Xiang Ziye, Xiong Pei, Liu Lianghong, Cai Wei, Chemical characterization of extracts of leaves of Kadsua coccinea (Lem.) A.C. Sm. by UHPLC-Q-Exactive Orbitrap Mass spectrometry and assessment of their antioxidant and anti-inflammatory activities, Biomedicine & Pharmacotherapy, 149, 2022. Crossref

  16. Ma Zihui, Liu Xiaoyan, Liu Yutong, Chen Wei, Wang Chengtao, Studies on the biosynthetic pathways of melanin in Auricularia auricula , Journal of Basic Microbiology, 62, 7, 2022. Crossref

  17. Pak SolJu, Chen Fang, Ma Lingjun, Hu Xiaosong, Ji Junfu, Functional perspective of black fungi (Auricularia auricula): Major bioactive components, health benefits and potential mechanisms, Trends in Food Science & Technology, 114, 2021. Crossref

  18. Boby Naila, Abbas Muhammad Aleem, Lee Eon-Bee, Im Zi-Eum, Lee Seung-Jin, Park Seung-Chun, Microbiota modulation and anti-obesity effects of fermented Pyrus ussuriensis Maxim extract against high-fat diet-induced obesity in rats, Biomedicine & Pharmacotherapy, 154, 2022. Crossref

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