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Journal of Environmental Pathology, Toxicology and Oncology
Factor de Impacto: 1.625 Factor de Impacto de 5 años: 1.63 SJR: 0.402 SNIP: 0.613 CiteScore™: 2.3

ISSN Imprimir: 0731-8898
ISSN En Línea: 2162-6537

Journal of Environmental Pathology, Toxicology and Oncology

DOI: 10.1615/JEnvironPatholToxicolOncol.2020033025
pages 159-177

Therapeutic Role of Natural Agents in the Management of Coronary Artery Disease: A Review

Ketan Vinayakrao Hatware
NMIMS, School of Pharmacy and Technology Management, Shirpur, Maharashtra, India, 425405
Sanjay Sharma
NMIMS, School of Pharmacy and Technology Management, Shirpur, Maharashtra, India, 425405
Kiran Patil
NMIMS, School of Pharmacy and Technology Management, Shirpur, Maharashtra, India, 425405
Harpalsing Rajput
NMIMS, School of Pharmacy and Technology Management, Shirpur, Maharashtra, India, 425405
Gaurav Gupta
School of Pharmacy, Suresh Gyan Vihar University, Jagatpura, 302017, Jaipur, India


This review delineates the potential of naturally occurring substances for coronary artery disease (CAD), mainly coronary ischemia and its management, with their active constituents and probable mechanisms of action. As per the WHO, statistical incidence of CAD has increased in several countries. The number of coronary events worldwide has been increasing, and may increase even more in the near future. Meanwhile, increased sedentary behavior and poor diet will encourage the prevalence of CAD worldwide. As far as treatment is concerned, current conventional therapies have limitations due to their increased adverse events. The current approach to the management of CAD has certain lacunas that need to be overcome. Thus, new therapeutic options should be explored using traditional literature and current scientific data on natural products. The present review article deals with current knowledge associated with naturally occurring substances for the management of CAD.


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