Suscripción a Biblioteca: Guest
Portal Digitalde Biblioteca Digital eLibros Revistas Referencias y Libros de Ponencias Colecciones
Journal of Environmental Pathology, Toxicology and Oncology
Factor de Impacto: 1.625 Factor de Impacto de 5 años: 1.63 SJR: 0.402 SNIP: 0.613 CiteScore™: 2.3

ISSN Imprimir: 0731-8898
ISSN En Línea: 2162-6537

Journal of Environmental Pathology, Toxicology and Oncology

DOI: 10.1615/JEnvironPatholToxicolOncol.v27.i3.10
pages 157-179

Computational Biology of Genome Expression and Regulation—A Review of Microarray Bioinformatics

Junbai Wang
Department of Pathology, The Norwegian Radium Hospital, Rikshospitalet University Hospital; Medical Faculty, University of Oslo, Oslo, Norway

SINOPSIS

Microarray technology is being used widely in various biomedical research areas; the corresponding microarray data analysis is an essential step toward the best utilizing of array technologies. Here we review two components of the microarray data analysis: a low level of microarray data analysis that emphasizes the designing, the quality control, and the preprocessing of microarray experiments, then a high level of microarray data analysis that focuses on the domain-specific microarray applications such as tumor classification, biomarker prediction, analyzing array CGH experiments, and reverse engineering of gene expression networks. Additionally, we will review the recent development of building a predictive model in genome expression and regulation studies. This review may help biologists grasp a basic knowledge of microarray bioinformatics as well as its potential impact on the future evolvement of biomedical research fields.


Articles with similar content:

Addressing the Translational Dilemma: Dynamic Knowledge Representation of Inflammation Using Agent-Based Modeling
Critical Reviews™ in Biomedical Engineering, Vol.40, 2012, issue 4
Scott Christley, Gary An
SEEING ONESELF AS A SCIENTIST: MEDIA INFLUENCES AND ADOLESCENT GIRLS' SCIENCE CAREER-POSSIBLE SELVES
Journal of Women and Minorities in Science and Engineering, Vol.15, 2009, issue 4
Lisa Ryan, Catherine Van Der Maas, Jocelyn Steinke, Marilee Long, Brooks Applegate, Maria Lapinski
Biomedical Research with Dual Use: Ethical Concerns
Ethics in Biology, Engineering and Medicine: An International Journal, Vol.6, 2015, issue 1-2
Simona loana Gheorghiu
Optochemotronic Sensors: New Elements for Biomedical Diagnostic Systems. 1. Basic Concepts, Theoretical Description, Physical and Mathematical Models of the Processes in Optochemotronic Sensors
Telecommunications and Radio Engineering, Vol.60, 2003, issue 3&4
N.N. Roshytsky, D.V. Snezhko
Therapeutic Genome Editing by CRISPR/Cas9-Mediated Strategy to Cure Genetic Disorders in Humans: Guide for Molecular Surgeons 
Critical Reviews™ in Eukaryotic Gene Expression, Vol.29, 2019, issue 5
Mahmut Cerkez Ergoren, Rida Idlibi