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Journal of Long-Term Effects of Medical Implants

Publicado 4 números por año

ISSN Imprimir: 1050-6934

ISSN En Línea: 1940-4379

SJR: 0.184 SNIP: 0.485 CiteScore™:: 1.1 H-Index: 39

Indexed in

Synergistic Effects of Implant Macrogeometry and Surface Physicochemical Modifications on Osseointegration: An In Vivo Experimental Study in Sheep

Volumen 29, Edición 4, 2019, pp. 295-302
DOI: 10.1615/JLongTermEffMedImplants.2020034194
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SINOPSIS

This study evaluates the influence of two surface physicochemical modifications on osseointegration parameters of a healing chamber implant design. We examine dental implants with internal and external trapezoidal threads that have the following surface modifications: dual acid etching (DAE) and nano-hydroxyapatite (HA) coating over DAE surface (Nano). We installed implants in the right ilium of sheep and conducted histologic/metric analyses after 3 and 12 wk in vivo. We quantified the percentage of bone-to-implant contact (%BIC) and bone area fraction occupancy (%BAFO) within implant threads. Histologic micrographs indicate early bone formation within the healing chambers of implants with Nano surface relative to DAE surface. Histomorphometric analysis demonstrates there to be no significant differences in %BIC between 3 and 12 wk (p = 0.298). Compared to DAE, Nano shows more bone formation in contact with implant, regardless of time (p < 0.025). We observe > %BAFO at 12 wk relative to 3 wk, which differs significantly for Nano (p < 0.038). Implant surface treatment affects the amounts of bone formation within healing chambers, with Nano significantly outperforming DAE at 12 wk (p < 0.025). Nano presents a synergistic effect with implant design, improving osseointegration parameters.

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CITADO POR
  1. Dong Heng, Liu Hui, Zhou Na, Li Qiang, Yang Guangwen, Chen Li, Mou Yongbin, Surface Modified Techniques and Emerging Functional Coating of Dental Implants, Coatings, 10, 11, 2020. Crossref

  2. Sun Yang, Zhang Xing, Luo Mingran, Hu Weifan, Zheng Li, Huang Ruqi, Greven Johannes, Hildebrand Frank, Yuan Feng, Plasma Spray vs. Electrochemical Deposition: Toward a Better Osteogenic Effect of Hydroxyapatite Coatings on 3D-Printed Titanium Scaffolds, Frontiers in Bioengineering and Biotechnology, 9, 2021. Crossref

  3. Benalcázar Jalkh Ernesto B., Parra Marcelo, Torroni Andrea, Nayak Vasudev Vivekanand, Tovar Nick, Castellano Arthur, Badalov Rafael M., Bonfante Estevam A., Coelho Paulo G., Witek Lukasz, Effect of supplemental acid-etching on the early stages of osseointegration: A preclinical model, Journal of the Mechanical Behavior of Biomedical Materials, 122, 2021. Crossref

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