Publicado 6 números por año
ISSN Imprimir: 1040-8401
ISSN En Línea: 2162-6472
Indexed in
Autoimmunity to Glutamate Receptors in the Central Nervous System
SINOPSIS
Autoimmunity to glutamate receptors (GluR) of the central nervous system offers an attractive model to begin the experimental dissection of the etiology of immune-related neurodegenerative diseases. Here we discuss the known mechanisms of generating autoimmunity to different members of the GluR neurotransmitter receptor family within the unique environment of the brain and how autoantibody-receptor interactions contribute to abnormal neurotransmission and eventually pathology.
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Levite Mia, Ganor Yonatan, Autoantibodies to glutamate receptors can damage the brain in epilepsy, systemic lupus erythematosus and encephalitis, Expert Review of Neurotherapeutics, 8, 7, 2008. Crossref
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Goldberg-Stern Hadassa, Ganor Yonatan, Cohen Ran, Pollak Lea, Teichberg Vivian, Levite Mia, Glutamate receptor antibodies directed against AMPA receptors subunit 3 peptide B (GluR3B) associate with some cognitive/psychiatric/behavioral abnormalities in epilepsy patients, Psychoneuroendocrinology, 40, 2014. Crossref
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Levite Mia, GLUTAMATE RECEPTOR ANTIBODIES IN NEUROLOGICAL DISEASES: Anti-AMPA-GluR3 antibodies, Anti-NMDA-NR1 antibodies, Anti-NMDA-NR2A/B antibodies, Anti-mGluR1 antibodies or Anti-mGluR5 antibodies are present in subpopulations of patients with either: Epilepsy, Encephalitis, Cerebellar Ataxia, Systemic Lupus Erythematosus (SLE) and Neuropsychiatric SLE, Sjogren’s syndrome, Schizophrenia, Mania or Stroke. These autoimmune anti-glutamate receptor antibodies can bind neurons in few brain regions, activate glutamate rec, Journal of Neural Transmission, 121, 8, 2014. Crossref
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Gahring Lorise C., Rogers Scott W., Neuronal nicotinic acetylcholine receptor expression and function on nonneuronal cells, The AAPS Journal, 7, 4, 2005. Crossref
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Gahring Lorise C., Days Emily L., Kaasch Tuesday, González de Mendoza Mónica, Owen Leah, Persiyanov Karina, Rogers Scott W., Pro-inflammatory cytokines modify neuronal nicotinic acetylcholine receptor assembly, Journal of Neuroimmunology, 166, 1-2, 2005. Crossref
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Diaz-parga Pedro, Goto Joy J., Krishnan V.V., Chemistry and Chemical Equilibrium Dynamics of BMAA and Its Carbamate Adducts, Neurotoxicity Research, 33, 1, 2018. Crossref
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Gahring Lorise C., Rogers Scott W., Neuronal Nicotinic Acetylcholine Receptor Expression and Function on Nonneuronal Cells, in Drug Addiction, 2008. Crossref
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Hampe Christiane S., Significance of Autoantibodies, in Neuroimmune Diseases, 2019. Crossref