Suscripción a Biblioteca: Guest
Portal Digitalde Biblioteca Digital eLibros Revistas Referencias y Libros de Ponencias Colecciones
Critical Reviews™ in Therapeutic Drug Carrier Systems
Factor de Impacto: 2.414 Factor de Impacto de 5 años: 3.324 SJR: 0.573 SNIP: 0.551 CiteScore™: 2.43

ISSN Imprimir: 0743-4863
ISSN En Línea: 2162-660X

Volumes:
Volumen 36, 2019 Volumen 35, 2018 Volumen 34, 2017 Volumen 33, 2016 Volumen 32, 2015 Volumen 31, 2014 Volumen 30, 2013 Volumen 29, 2012 Volumen 28, 2011 Volumen 27, 2010 Volumen 26, 2009 Volumen 25, 2008 Volumen 24, 2007 Volumen 23, 2006 Volumen 22, 2005 Volumen 21, 2004 Volumen 20, 2003 Volumen 19, 2002 Volumen 18, 2001 Volumen 17, 2000 Volumen 16, 1999 Volumen 15, 1998 Volumen 14, 1997 Volumen 13, 1996 Volumen 12, 1995

Critical Reviews™ in Therapeutic Drug Carrier Systems

DOI: 10.1615/CritRevTherDrugCarrierSyst.2014008126
pages 219-272

Novel Strategies for Effective Transdermal Drug Delivery: A Review

Ankita Jain
Pharmaceutics Research Laboratory, Department of Pharmaceutics, Adina Institute of Pharmaceutical Sciences, Sagar (M.P.), 470002 India
Priyanka Jain
Pharmaceutics Research Laboratory, Department of Pharmaceutics, Adina Institute of Pharmaceutical Sciences, Sagar (M.P.), 470002 India
Jaya Kurmi
Pharmaceutics Research Laboratory, Department of Pharmaceutics, Adina Institute of Pharmaceutical Sciences, Sagar (M.P.), 470002 India
Darshana Jain
Pharmaceutics Research Laboratory, Department of Pharmaceutics, Adina Institute of Pharmaceutical Sciences, Sagar (M.P.), 470002 India
Roshni Jain
Pharmaceutics Research Laboratory, Department of Pharmaceutics, Adina Institute of Pharmaceutical Sciences, Sagar (M.P.), 470002 India
Silky Chandel
Pharmaceutics Research Laboratory, Department of Pharmaceutics, Adina Institute of Pharmaceutical Sciences, Sagar (M.P.), 470002 India
Anamika Sahu
Pharmaceutics Research Laboratory, Department of Pharmaceutics, Adina Institute of Pharmaceutical Sciences, Sagar (M.P.), 470002 India
Nishi Mody
Pharmaceutics Research Laboratory, Department of Pharmaceutics, Adina Institute of Pharmaceutical Sciences, Sagar (M.P.), 470002 India
Satish Upadhaya
Pharmaceutics Research Laboratory, Department of Pharmaceutics, Adina Institute of Pharmaceutical Sciences, Sagar (M.P.), 470002 India
Aviral Jain
Pharmaceutics Research Projects Laboratory, Department of Pharmaceutical Sciences, Dr. Hari Singh Gour Vishwavidyalaya, Sagar (M. P.) 470003, India

SINOPSIS

Skin is the largest and easily accessible organ of the body and therefore can be extensively used as a prominent route of delivery for local and systemic effects. Though it presents a multifunctional barrier between body and surrounding particles, there are chances to deliver therapeutic nanocarrier, particularly in diseased skin. Both for dermal and transdermal drug delivery, the horny layer, i.e., the uppermost layer of the skin serve as the most resistant layer to be crossed and for this purpose, different perforation techniques are used that relatively widen the skin opening and allow the passage of drug (≤ 10 mg) and micromolecules, but this amateur disruption of the skin can be avoided in order to preserve this barrier against cutaneous microbiota by using deformable nanocarriers. In this review, we discuss the nanosized aggregates and microneedle technology for the advanced delivery of vaccines, protein, peptides, nucleic acid, and hormone across the skin.


Articles with similar content:

Ligand-Appended BBB-Targeted Nanocarriers (LABTNs)
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.32, 2015, issue 2
Ankit Jain, Sanjay Kumar Jain
Bioerodible Polymers for Ocular Drug Delivery
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.15, 1998, issue 4
R. Gurny, J. Heller, A. A. Deshpande
Stimuli-Sensitive Hydrogels: An Excellent Carrier for Drug and Cell Delivery
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.30, 2013, issue 5
Simranjit Singh, Tarun Garg, Amit Kumar Goyal
Gene Delivery Using Lipoplexes and Polyplexes: Principles, Limitations and Solutions
Critical Reviews™ in Eukaryotic Gene Expression, Vol.29, 2019, issue 1
Amir Roointan, Najmeh Farahani, Esmat Safdarian, Seyed Mohammad Gheibi Hayat, Amirhossein Sahebkar
Polyphosphates and Other Phosphorus-Containing Polymers for Drug Delivery Applications
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.20, 2003, issue 4
Stephanie T. Lopina, Duane F. Bruley, Mahesh V. Chaubal, Anirban Sen Gupta