Publicado 6 números por año
ISSN Imprimir: 0743-4863
ISSN En Línea: 2162-660X
Indexed in
Current Nanotechnological Strategies for Effective Delivery of Bioactive Drug Molecules in the Treatment of Tuberculosis
SINOPSIS
Tuberculosis (TB) has gone from being a forgotten disease to a modern and recrudescent pathology from past decades. Some clinical problems and challenges associated with conventional TB chemotherapy include poor patient compliance, longer duration of chemotherapy, lesser cell permeability, primary drug resistance, difficulty in maintaining higher drug concentrations at the infected site, and degradation of the drug before reaching the target site. Thus, newer drug delivery approaches involving micrometric or nanometric carriers are needed. These delivery systems should provide advantages over conventional systems by producing optimum effectiveness to the target site, enhanced therapeutic efficacy, uniform distribution of the drug throughout the target site, increased bioavailability and sustainability of the drug, fewer side effects, and increased patient compliance. This article reviews recent updates and fabrication of drug delivery approaches for tuberculosis chemotherapy involving vesicular drug delivery systems (liposomes, niosomes, solid lipid nanoparticles), particulate drug delivery systems (nanoparticles, microparticles, dendrimers), supramolecular drug delivery systems (polymeric micelles), specialized drug delivery systems (nanosuspensions, nanoemulsions, microemulsions, dry powders), complex conjugate drug delivery systems (ISCOMs, cyclodextrin inclusion complexes), and other carrier-based drug delivery systems in order to improve patient outcomes.
-
Kaur Ranjot, Garg Tarun, Malik Basant, Gupta Umesh Datta, Gupta Pushpa, Rath Goutam, Goyal Amit Kumar, Development and characterization of spray-dried porous nanoaggregates for pulmonary delivery of anti-tubercular drugs, Drug Delivery, 23, 3, 2016. Crossref
-
Rohilla Raman, Garg Tarun, Bariwal Jitender, Goyal Amit K., Rath Goutam, Development, optimization and characterization of glycyrrhetinic acid–chitosan nanoparticles of atorvastatin for liver targeting, Drug Delivery, 23, 7, 2016. Crossref
-
Malik Rafi, Garg Tarun, Goyal Amit K., Rath Goutam, Polymeric nanofibers: targeted gastro-retentive drug delivery systems, Journal of Drug Targeting, 23, 2, 2015. Crossref
-
Marwah Harneet, Garg Tarun, Goyal Amit K., Rath Goutam, Permeation enhancer strategies in transdermal drug delivery, Drug Delivery, 23, 2, 2016. Crossref
-
Johal Himmat Singh, Garg Tarun, Rath Goutam, Goyal Amit Kumar, Advanced topical drug delivery system for the management of vaginal candidiasis, Drug Delivery, 23, 2, 2016. Crossref
-
Kaur Prabhjot, Garg Tarun, Vaidya Bhuvaneshwar, Prakash Atish, Rath Goutam, Goyal Amit K., Brain delivery of intranasalin situgel of nanoparticulated polymeric carriers containing antidepressant drug: behavioral and biochemical assessment, Journal of Drug Targeting, 23, 3, 2015. Crossref
-
Garg Tarun, Rath Goutam, Goyal Amit K., Biomaterials-based nanofiber scaffold: targeted and controlled carrier for cell and drug delivery, Journal of Drug Targeting, 23, 3, 2015. Crossref
-
Kalia Vani, Garg Tarun, Rath Gautam, Goyal Amit Kumar, Development and evaluation of a sublingual film of the antiemetic granisetron hydrochloride, Artificial Cells, Nanomedicine, and Biotechnology, 2014. Crossref
-
Rohilla Raman, Garg Tarun, Goyal Amit K., Rath Goutam, Herbal and polymeric approaches for liver-targeting drug delivery: novel strategies and their significance, Drug Delivery, 2014. Crossref
-
Joshi Deeksha, Garg Tarun, Goyal Amit K., Rath Goutam, Advanced drug delivery approaches against periodontitis, Drug Delivery, 23, 2, 2016. Crossref
-
Kaur Navdeep, Garg Tarun, Goyal Amit K., Rath Goutam, Formulation, optimization and evaluation of curcumin-β-cyclodextrin-loaded sponge for effective drug delivery in thermal burns chemotherapy, Drug Delivery, 23, 7, 2016. Crossref
-
Kaur Prabhjot, Garg Tarun, Rath Goutam, Murthy R. S. R., Goyal Amit K., Surfactant-based drug delivery systems for treating drug-resistant lung cancer, Drug Delivery, 23, 3, 2016. Crossref
-
Chaudhary Shilpa, Garg Tarun, Murthy R. S. R., Rath Goutam, Goyal Amit K., Recent approaches of lipid-based delivery system for lymphatic targeting via oral route, Journal of Drug Targeting, 22, 10, 2014. Crossref
-
Kaur Prabhjot, Garg Tarun, Rath Goutam, Murthy R. S. Rayasa, Goyal Amit K., Development, optimization and evaluation of surfactant-based pulmonary nanolipid carrier system of paclitaxel for the management of drug resistance lung cancer using Box-Behnken design, Drug Delivery, 2014. Crossref
-
Rath Goutam, Hussain Taqadus, Chauhan Gaurav, Garg Tarun, Kumar Goyal Amit, Fabrication and characterization of cefazolin-loaded nanofibrous mats for the recovery of post-surgical wound, Artificial Cells, Nanomedicine, and Biotechnology, 44, 8, 2016. Crossref
-
Sharma Aman Kumar, Garg Tarun, Goyal Amit K., Rath Goutam, Role of microemuslsions in advanced drug delivery, Artificial Cells, Nanomedicine, and Biotechnology, 2015. Crossref
-
Malik Raffi, Garg Tarun, Goyal Amit K., Rath Goutam, Diacerein-Loaded novel gastroretentive nanofiber system using PLLA: Development andin vitrocharacterization, Artificial Cells, Nanomedicine, and Biotechnology, 2015. Crossref
-
Kaur Prabhjot, Garg Tarun, Rath Goutam, Goyal Amit K., In situ nasal gel drug delivery: A novel approach for brain targeting through the mucosal membrane, Artificial Cells, Nanomedicine, and Biotechnology, 2015. Crossref
-
Kaur Gurmeet, Garg Tarun, Rath Goutam, Goyal Amit K., Archaeosomes: an excellent carrier for drug and cell delivery, Drug Delivery, 23, 7, 2016. Crossref
-
Garg Tarun, Rath Goutam, Goyal Amit K., Inhalable chitosan nanoparticles as antitubercular drug carriers for an effective treatment of tuberculosis, Artificial Cells, Nanomedicine, and Biotechnology, 2015. Crossref
-
Chaudhary Sushant, Garg Tarun, Rath Goutam, Murthy Rs Rayasa, Goyal Amit K., Enhancing the bioavailability of mebendazole by integrating the principles solid dispersion and nanocrystal techniques, for safe and effective management of human echinococcosis, Artificial Cells, Nanomedicine, and Biotechnology, 2015. Crossref
-
Ishikawa Aline A., Velazquez Salazar J. Jesus, Salinas Magaly, Gaitani Cristiane M., Nurkiewicz Timothy R., Negrete George R., Garcia Carlos D., Self-assembled nanospheres for encapsulation and aerosolization of rifampicin, RSC Advances, 6, 16, 2016. Crossref
-
Singh Jagdeep, Garg Tarun, Rath Goutam, Goyal Amit K., Advances in nanotechnology-based carrier systems for targeted delivery of bioactive drug molecules with special emphasis on immunotherapy in drug resistant tuberculosis – a critical review, Drug Delivery, 23, 5, 2016. Crossref
-
Garg Tarun, Goyal Amit K., Rath Goutam, Murthy R. S. R., Spray-dried particles as pulmonary delivery system of anti-tubercular drugs: design, optimization, in vitro and in vivo evaluation, Pharmaceutical Development and Technology, 21, 8, 2016. Crossref
-
Chassot Janaíne Micheli, Ferreira Luana Mota, Gomes Felipe Pereira, Silva Cristiane de Bona da, Tasso Leandro, Cruz Letícia, Pullulan as a stabilizer agent of polymeric nanocapsules for drug delivery, Brazilian Journal of Pharmaceutical Sciences, 52, 4, 2016. Crossref
-
Morales-Avila Enrique, Ferro-Flores Guillermina, Ocampo-García Blanca E., López-Téllez Gustavo, López-Ortega Johnny, Rogel-Ayala Diana G., Sánchez-Padilla Diego, Antibacterial Efficacy of Gold and Silver Nanoparticles Functionalized with the Ubiquicidin (29–41) Antimicrobial Peptide, Journal of Nanomaterials, 2017, 2017. Crossref
-
Verma Anurakshee, Riaz Ufana, Mechanochemically synthesized poly(o-toluidine)-intercalated montmorillonite nanocomposites as antituberculosis drug carriers, International Journal of Polymeric Materials and Polymeric Biomaterials, 67, 4, 2018. Crossref
-
Zaidi Sahar, Misba Lama, Khan Asad U, Nano-therapeutics: A revolution in infection control in post antibiotic era, Nanomedicine: Nanotechnology, Biology and Medicine, 13, 7, 2017. Crossref
-
Islan German A., Durán Marcela, Cacicedo Maximiliano L., Nakazato Gerson, Kobayashi Renata K.T., Martinez Diego S.T., Castro Guillermo R., Durán Nelson, Nanopharmaceuticals as a solution to neglected diseases: Is it possible?, Acta Tropica, 170, 2017. Crossref
-
Goyal Amit K., Garg Tarun, Bhandari Sourav, Rath Goutam, Advancement in pulmonary drug delivery systems for treatment of tuberculosis, in Nanostructures for Drug Delivery, 2017. Crossref
-
de Souza Márcia E., Verdi Camila M., de Andrade Eduardo N.C., Santos Roberto C.V., Antiviral and Antimicrobial (Antibacterial) Potentiality of Nano Drugs, in Applications of Targeted Nano Drugs and Delivery Systems, 2019. Crossref
-
Setia Anupama, Ahuja Priyanka, Nanohydrogels, in Organic Materials as Smart Nanocarriers for Drug Delivery, 2018. Crossref
-
Jalaei Jafar, Layeghi-Ghalehsoukhteh Somayeh, Hosseini Arsalan, Fazeli Mehdi, Antibacterial effects of gold nanoparticles functionalized with the extracted peptide fromVespa orientaliswasp venom, Journal of Peptide Science, 24, 12, 2018. Crossref
-
Dhiman Mamta, Singh Abhijeet, Sharma Madan Mohan, A review on Sterculia urens Roxb.: a boon to the livelihood for tribal people and industry, Industrial Crops and Products, 130, 2019. Crossref
-
Suhail Muhammad, Rosenholm Jessica M, Minhas Muhammad Usman, Badshah Syed Faisal, Naeem Abid, Khan Kifayat Ullah, Fahad Muhammad, Nanogels as drug-delivery systems: a comprehensive overview, Therapeutic Delivery, 10, 11, 2019. Crossref
-
Das Subhraseema, Subuddhi Usharani, Potential of guar gum hydrogels in drug delivery, in Plant and Algal Hydrogels for Drug Delivery and Regenerative Medicine, 2021. Crossref
-
Bhat Medha, Pukale Sudeep, Singh Saurabh, Mittal Anupama, Chitkara Deepak, Nano-enabled topical delivery of anti-psoriatic small molecules, Journal of Drug Delivery Science and Technology, 62, 2021. Crossref
-
Goyal Amit Kumar, Garg Tarun, Rath Goutam, Gupta Umesh Datta, Gupta Pushpa, Development and Characterization of Nanoembedded Microparticles for Pulmonary Delivery of Antitubercular Drugs against Experimental Tuberculosis, Molecular Pharmaceutics, 12, 11, 2015. Crossref
-
Sharma Kapil, Clinical perspectives of nanotherapy in tuberculosis treatment, in A Mechanistic Approach to Medicines for Tuberculosis Nanotherapy, 2021. Crossref
-
Kankala Ranjith Kumar, Lin Xiao-Fen, Song Hu-Fan, Wang Shi-Bin, Yang Da-Yun, Zhang Yu Shrike, Chen Ai-Zheng, Supercritical Fluid-Assisted Decoration of Nanoparticles on Porous Microcontainers for Codelivery of Therapeutics and Inhalation Therapy of Diabetes, ACS Biomaterials Science & Engineering, 4, 12, 2018. Crossref
-
Dua Kamal, Rapalli Vamshi Krishna, Shukla Shakti Dhar, Singhvi Gautam, Shastri Madhur D., Chellappan Dinesh Kumar, Satija Saurabh, Mehta Meenu, Gulati Monica, Pinto Terezinha De Jesus Andreoli, Gupta Gaurav, Hansbro Philip M., Multi-drug resistant Mycobacterium tuberculosis & oxidative stress complexity: Emerging need for novel drug delivery approaches, Biomedicine & Pharmacotherapy, 107, 2018. Crossref
-
Shahid SK, Newer patents in antimycobacterial therapy, Pharmaceutical Patent Analyst, 4, 3, 2015. Crossref
-
Prasad Niranjan, Thombare Nandkishore, Sharma Satish Chandra, Kumar Shravan, Production, processing, properties and applications of karaya (Sterculia species) gum, Industrial Crops and Products, 177, 2022. Crossref
-
Sharma Ankita, Garg Tarun, Aman Amrinder, Panchal Kushan, Sharma Rajiv, Kumar Sahil, Markandeywar Tanmay, Nanogel—an advanced drug delivery tool: Current and future, Artificial Cells, Nanomedicine, and Biotechnology, 44, 1, 2016. Crossref
-
Morie Asif, Garg Tarun, Goyal Amit K., Rath Goutam, Nanofibers as novel drug carrier – An overview, Artificial Cells, Nanomedicine, and Biotechnology, 44, 1, 2016. Crossref
-
Santos Filipa, Duarte Ana Rita C., Combination drug delivery approaches for tuberculosis, in Combination Drug Delivery Approach as an Effective Therapy for Various Diseases, 2022. Crossref
-
da Silva Leite Joandra Maísa, Patriota Yuri Basilio Gomes, de La Roca Mônica Felts, Soares-Sobrinho José Lamartine, New Perspectives in Drug Delivery Systems for the Treatment of Tuberculosis, Current Medicinal Chemistry, 29, 11, 2022. Crossref
-
Sharma Rahul, Garg Tarun, Goyal Amit K., Rath Goutam, Development, optimization and evaluation of polymeric electrospun nanofiber: A tool for local delivery of fluconazole for management of vaginal candidiasis, Artificial Cells, Nanomedicine, and Biotechnology, 44, 2, 2016. Crossref
-
Prasad Niranjan, Thombare Nandkishore, Sharma S. C., Kumar Shravan, Recent development in the medical and industrial applications of gum karaya: a review, Polymer Bulletin, 2022. Crossref
-
Zazo Hinojal, Colino Clara I., Lanao José M., Current applications of nanoparticles in infectious diseases, Journal of Controlled Release, 224, 2016. Crossref
-
Rath Goutam, Pradhan Deepak, Ghosh Goutam, Goyal Amit K., Challenges and Opportunities of Nanotechnological based Approach for the Treatment of Tuberculosis, Current Pharmaceutical Design, 27, 17, 2021. Crossref
-
Kaur Manpreet, Garg Tarun, Narang R. K., A review of emerging trends in the treatment of tuberculosis, Artificial Cells, Nanomedicine, and Biotechnology, 44, 2, 2016. Crossref
-
Shah Sunny, Maheshwari Hiren, Soniwala Moinuddin, Chavda Jayant, Pulmonary Delivery of Linezolid Nanoparticles for Treatment of Tuberculosis: Design, Development, and Optimization, Journal of Pharmaceutical Innovation, 17, 1, 2022. Crossref
-
Kaur Ranjot, Garg Tarun, Das Gupta Umesh, Gupta Pushpa, Rath Goutam, Goyal Amit Kumar, Preparation and characterization of spray-dried inhalable powders containing nanoaggregates for pulmonary delivery of anti-tubercular drugs, Artificial Cells, Nanomedicine, and Biotechnology, 44, 1, 2016. Crossref
-
Singh Baljeet, Garg Tarun, Goyal Amit K., Rath Goutam, Recent advancements in the cardiovascular drug carriers, Artificial Cells, Nanomedicine, and Biotechnology, 44, 1, 2016. Crossref
-
Modgill Vedant, Garg Tarun, Goyal Amit Kumar, Rath Goutam, Permeability study of ciprofloxacin from ultra-thin nanofibrous film through various mucosal membranes, Artificial Cells, Nanomedicine, and Biotechnology, 44, 1, 2016. Crossref
-
Pabreja Swati, Garg Tarun, Rath Goutam, Goyal Amit K., Mucosal vaccination against tuberculosis using Ag85A-loaded immunostimulating complexes, Artificial Cells, Nanomedicine, and Biotechnology, 44, 2, 2016. Crossref
-
Singh Baljeet, Garg Tarun, Goyal Amit K., Rath Goutam, Development, optimization, and characterization of polymeric electrospun nanofiber: a new attempt in sublingual delivery of nicorandil for the management of angina pectoris, Artificial Cells, Nanomedicine, and Biotechnology, 44, 6, 2016. Crossref
-
Garg Tarun, Rath Goutam, Goyal Amit K., Nanotechnological approaches for the effective management of psoriasis, Artificial Cells, Nanomedicine, and Biotechnology, 44, 6, 2016. Crossref
-
Shah Sunny, Cristopher Dhanya, Sharma Shweta, Soniwala Moinuddin, Chavda Jayant, Inhalable linezolid loaded PLGA nanoparticles for treatment of tuberculosis: Design, development and in vitro evaluation, Journal of Drug Delivery Science and Technology, 60, 2020. Crossref
-
Ali Faraat, Neha Kumari, Sharma Kamna, Khasimbi Shaik, Chauhan Garima, Nanotechnology-based Medicinal Products and Patents: A Promising Way to Treat Psoriasis, Current Drug Delivery, 19, 5, 2022. Crossref
-
Attama Anthony A., Nnamani Petra O., Onokala Ozioma B., Ugwu Agatha A., Onugwu Adaeze L., Nanogels as target drug delivery systems in cancer therapy: A review of the last decade, Frontiers in Pharmacology, 13, 2022. Crossref
-
Chopra Hitesh, Verma Ravinder , Kaushik Sakshi , Parashar Jatin , Madan Kumud , Bano Afsareen , Bhardwaj Rashmi , Pandey Parijat , Kumari Beena , Purohit Deepika , Kumar Manish , Bhatia Saurabh , Rahman Md. Habibur , Mittal Vineet, Singh Inderbir , Kaushik Deepak, Cyclodextrin-Based Arsenal for Anti-Cancer Treatments , Critical Reviews™ in Therapeutic Drug Carrier Systems, 40, 2, 2023. Crossref