Suscripción a Biblioteca: Guest
Portal Digitalde Biblioteca Digital eLibros Revistas Referencias y Libros de Ponencias Colecciones
Critical Reviews™ in Therapeutic Drug Carrier Systems
Factor de Impacto: 2.9 Factor de Impacto de 5 años: 3.72 SJR: 0.736 SNIP: 0.551 CiteScore™: 2.43

ISSN Imprimir: 0743-4863
ISSN En Línea: 2162-660X

Volumes:
Volumen 36, 2019 Volumen 35, 2018 Volumen 34, 2017 Volumen 33, 2016 Volumen 32, 2015 Volumen 31, 2014 Volumen 30, 2013 Volumen 29, 2012 Volumen 28, 2011 Volumen 27, 2010 Volumen 26, 2009 Volumen 25, 2008 Volumen 24, 2007 Volumen 23, 2006 Volumen 22, 2005 Volumen 21, 2004 Volumen 20, 2003 Volumen 19, 2002 Volumen 18, 2001 Volumen 17, 2000 Volumen 16, 1999 Volumen 15, 1998 Volumen 14, 1997 Volumen 13, 1996 Volumen 12, 1995

Critical Reviews™ in Therapeutic Drug Carrier Systems

DOI: 10.1615/CritRevTherDrugCarrierSyst.v23.i6.20
pages 497-523

Lipoproteins: From Physiological Roles to Drug Delivery Potentials

Mehrdad Hamidi
Department of Pharmaceutics, School of Pharmacy, Zanjan University of Medical Science
Mahshid Foroozesh
Department of Pharmaceutics, Faculty of Pharmacy, Shiraz University of Medical Sciences, P.O. BOX 71345-1583, Shiraz, Iran
Abdolhossein Zarrin
Department of Pharmaceutics, Faculty of Pharmacy, Shiraz University of Medical Sciences, P.O. BOX 71345-1583, Shiraz, Iran

SINOPSIS

Lipoproteins, the endogenous lipid-protein associations responsible for lipid metabolism within the human body, have attracted interest in recent years for their potential as drug delivery carriers owing to, mainly, their lipophilic/amphiphilic nature, which makes them ideal for interacting with highly lipophilic drugs. After lipoprotein particles have been isolated from the blood, drugs can be "loaded" onto them with a variety of methods. Loading can be done either in soluble/suspended form in a liquid medium or as a dry film. Each method has advantages and disadvantages. The drug-loaded lipoproteins can be modified by the attachment of different ligands that target the particles to specific tissue/cell types within the body. A wide variety of drug molecules both from small molecular or macromolecular structures have been tested successfully, mostly in vitro, for their potential for delivery by lipoprotein carriers.


Articles with similar content:

PLGA Nanoparticles in Drug Delivery: The State of the Art
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.21, 2004, issue 5
Sarita Hariharan, Indu Bala, M. N. V. Ravi Kumar
Pharmaceutical and Biomedical Potential of Surface Engineered Dendrimers
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.24, 2007, issue 3
Narendra Kumar Jain, Umesh Gupta, Jitendra Satija
Shielding Therapeutic Drug Carriers from the Mononuclear Phagocyte System: A Review
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.33, 2016, issue 6
Magharla Dasaratha Dhanaraju, Nandhakumar Sathyamoorthy
Mannosylated Constructs as a Platform for Cell-Specific Delivery of Bioactive Agents
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.35, 2018, issue 2
Sanjay Tiwari
Azo Chemistry and Its Potential for Colonic Delivery
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.23, 2006, issue 5
Yashwant Gupta, Anekant Jain, Sanjay Kumar Jain