Publicado 6 números por año
ISSN Imprimir: 0743-4863
ISSN En Línea: 2162-660X
Indexed in
Inorganic Nanoparticles for X-Ray Computed Tomography Imaging
SINOPSIS
In the last two decades, nanoparticle contrast agents have emerged as an essential tool for preclinical imaging and diagnosis. Besides their main advantage, related to their size range inhibiting glomerular filtration, they exhibit excellent X-ray attenuation when fabricated with heavy metal and thus high contrast in tomodensitometry. Another strength of inorganic nanoparticles, making them very adaptable to preclinical imaging applications, is the modularity of their surface chemistry, which is compatible with decoration by ligands and biomolecules. The present review draws a state-of-the art picture of the different inorganic nanoparticles synthesized as X-ray contrast agents. We present the panel of heavy metals and materials used, their X-ray attenuation properties, related applications, potential surface modifications, and in vitro and in vivo behaviors. An important aspect of this review is that the majority of inorganic nanoparticles are based on gold. We summarize the latest technologies for targeting nanoparticles designed to improve imaging techniques and advanced diagnostic methods.
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Attia Mohamed F., Ranasinghe Meenakshi, Akasov Roman, Anker Jeffrey N., Whitehead Daniel C., Alexis Frank, In situ preparation of gold–polyester nanoparticles for biomedical imaging, Biomaterials Science, 8, 11, 2020. Crossref
-
Shahbazi Mohammad-Ali, Faghfouri Leila, Ferreira Mónica P. A., Figueiredo Patrícia, Maleki Hajar, Sefat Farshid, Hirvonen Jouni, Santos Hélder A., The versatile biomedical applications of bismuth-based nanoparticles and composites: therapeutic, diagnostic, biosensing, and regenerative properties, Chemical Society Reviews, 49, 4, 2020. Crossref
-
Jiang Yuyan, Pu Kanyi, Molecular Probes for Autofluorescence-Free Optical Imaging, Chemical Reviews, 121, 21, 2021. Crossref
-
Lawson Taylor B., Mäkelä Janne T.A., Klein Travis, Snyder Brian D., Grinstaff Mark W., Nanotechnology and Osteoarthritis. Part 1: Clinical landscape and opportunities for advanced diagnostics, Journal of Orthopaedic Research, 39, 3, 2021. Crossref
-
Lawson Taylor, Joenathan Anisha, Patwa Amit, Snyder Brian D., Grinstaff Mark W., Tantalum Oxide Nanoparticles for the Quantitative Contrast-Enhanced Computed Tomography of Ex Vivo Human Cartilage: Assessment of Biochemical Composition and Biomechanics, ACS Nano, 15, 12, 2021. Crossref
-
Barry Edward, Burns Raelyn, Chen Wei, De Hoe Guilhem X., De Oca Joan Manuel Montes, de Pablo Juan J., Dombrowski James, Elam Jeffrey W., Felts Alanna M., Galli Giulia, Hack John, He Qiming, He Xiang, Hoenig Eli, Iscen Aysenur, Kash Benjamin, Kung Harold H., Lewis Nicholas H. C., Liu Chong, Ma Xinyou, Mane Anil, Martinson Alex B. F., Mulfort Karen L., Murphy Julia, Mølhave Kristian, Nealey Paul, Qiao Yijun, Rozyyev Vepa, Schatz George C., Sibener Steven J., Talapin Dmitri, Tiede David M., Tirrell Matthew V., Tokmakoff Andrei, Voth Gregory A., Wang Zhongyang, Ye Zifan, Yesibolati Murat, Zaluzec Nestor J., Darling Seth B., Advanced Materials for Energy-Water Systems: The Central Role of Water/Solid Interfaces in Adsorption, Reactivity, and Transport, Chemical Reviews, 121, 15, 2021. Crossref
-
Molkenova A., Atabaev T.S., Hong S.W., Mao C., Han D.-W., Kim K.S., Designing inorganic nanoparticles into computed tomography and magnetic resonance (CT/MR) imaging-guidable photomedicines, Materials Today Nano, 18, 2022. Crossref
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Corbin Brooke A., Lutter Jacob C., White Susan A., Al-ani Enas, Biros Elizabeth S., Karns John P., Allen Matthew J., Imaging, in Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, 2022. Crossref