Suscripción a Biblioteca: Guest
Portal Digitalde Biblioteca Digital eLibros Revistas Referencias y Libros de Ponencias Colecciones
Critical Reviews™ in Biomedical Engineering
SJR: 0.26 SNIP: 0.375 CiteScore™: 1.4

ISSN Imprimir: 0278-940X
ISSN En Línea: 1943-619X

Volumen 48, 2020 Volumen 47, 2019 Volumen 46, 2018 Volumen 45, 2017 Volumen 44, 2016 Volumen 43, 2015 Volumen 42, 2014 Volumen 41, 2013 Volumen 40, 2012 Volumen 39, 2011 Volumen 38, 2010 Volumen 37, 2009 Volumen 36, 2008 Volumen 35, 2007 Volumen 34, 2006 Volumen 33, 2005 Volumen 32, 2004 Volumen 31, 2003 Volumen 30, 2002 Volumen 29, 2001 Volumen 28, 2000 Volumen 27, 1999 Volumen 26, 1998 Volumen 25, 1997 Volumen 24, 1996 Volumen 23, 1995

Critical Reviews™ in Biomedical Engineering

DOI: 10.1615/CritRevBiomedEng.2012006777
pages 441-456

Next Generation Long-Term Mechanical Circulatory Support Systems: Are Pulsatile Pumps Extinct? Challenges, Goals, and Opportunities

Hisham M. F. Sherif
Cardiac Surgery, Christiana Hospital, 4755 Ogletown-Stanton Road, Newark, DE 19718; Department of Biomedical Engineering, University of Delaware, Newark, DE 19711


The therapeutic value of mechanically assisted circulation in the management of end-stage congestive heart failure has been shown. However, the ideal mechanical circulatory support device has not been introduced, especially for long-term or permanent use. Such a device should be durable, completely implantable, autonomous, small in size, and easy to use; it should provide a physiologic perfusion pattern. Current trends have favored non-pulsatile or continuous-flow devices over the older pulsatile devices. There has been no significant innovation in pulsatile devices for over 10 years. There is an ongoing debate about the physiologic impact of non-pulsatile flow. We explore the physiologic impact, biocompatibility issues, challenges in energy management, mechanical efficiency, and implantable power sources that exist in developing new classes of pulsatile devices for long-term mechanical circulatory support.

Articles with similar content:

Composite Resin in Medicine and Dentistry
Journal of Long-Term Effects of Medical Implants, Vol.15, 2005, issue 6
Jennifer Sullivan, Paul B. Osborne, Pamela S. Stein, James E. Haubenreich
Efficacy of Combined Magnetic Field Treatment on Spinal Fusion: A Review of the Literature
Journal of Long-Term Effects of Medical Implants, Vol.26, 2016, issue 3
Sheila Sprague, Mark Phillips, Ilyas Aleem, Brian Drew
Cardiac Implantable Electronic Device Infections: The Enemy That Lurks Beneath the Skin
Journal of Long-Term Effects of Medical Implants, Vol.20, 2010, issue 3
Ronan Margey
Back Problems in Health Professionals: Extent of the Problem and an Integrated Approach for Its Management
Critical Reviews™ in Physical and Rehabilitation Medicine, Vol.8, 1996, issue 3
Donald E. Shrey, Anil Mital
Vibration Arthrometry: A Critical Review
Critical Reviews™ in Biomedical Engineering, Vol.41, 2013, issue 3
Michael D Cole, Steven C Abbott