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Critical Reviews™ in Biomedical Engineering
SJR: 0.243 SNIP: 0.376 CiteScore™: 0.79

ISSN Imprimir: 0278-940X
ISSN En Línea: 1943-619X

Volumes:
Volumen 46, 2018 Volumen 45, 2017 Volumen 44, 2016 Volumen 43, 2015 Volumen 42, 2014 Volumen 41, 2013 Volumen 40, 2012 Volumen 39, 2011 Volumen 38, 2010 Volumen 37, 2009 Volumen 36, 2008 Volumen 35, 2007 Volumen 34, 2006 Volumen 33, 2005 Volumen 32, 2004 Volumen 31, 2003 Volumen 30, 2002 Volumen 29, 2001 Volumen 28, 2000 Volumen 27, 1999 Volumen 26, 1998 Volumen 25, 1997 Volumen 24, 1996 Volumen 23, 1995

Critical Reviews™ in Biomedical Engineering

DOI: 10.1615/CritRevBiomedEng.2016016448
pages 277-296

Biomedical Applications of Quantum Dots, Nucleic Acid−Based Aptamers, and Nanostructures in Biosensors

Xenia Meshik
Bioengineering Department, University of Illinois at Chicago
Sidra Farid
Electrical & Computer Engineering Department, University of Illinois at Chicago
Min Choi
Electrical & Computer Engineering Department, University of Illinois at Chicago
Yi Lan
Electrical & Computer Engineering Department, University of Illinois at Chicago
Souvik Mukherjee
Electrical & Computer Engineering Department, University of Illinois at Chicago
Debopam Datta
Electrical & Computer Engineering Department, University of Illinois at Chicago
Mitra Dutta
Bioengineering Department, University of Illinois at Chicago; Physics Department, University of Illinois at Chicago
Michael A. Stroscio
Bioengineering Department, University of Illinois at Chicago; Electrical & Computer Engineering Department, University of Illinois at Chicago; Physics Department, University of Illinois at Chicago

SINOPSIS

This review is a survey of the biomedical applications of semiconductor quantum dots, nucleic acid−based aptamers, and nanosensors as molecular biosensors. It focuses on the detection of analytes in biomedical applications using (1) advances in molecular beacons incorporating semiconductor quantum dots and nanoscale quenching elements; (2) aptamer-based nanosensors on a variety of platforms, including graphene; (3) Raman scattering and surface-enhanced Raman scattering (SERS) using nanostructures for enhanced SERS spectra of biomolecules, including aptamers; and (4) the electrical and optical properties of nanostructures incorporated into molecular beacons and aptamer-based nanosensors. Research done at the University of Illinois at Chicago (UIC) is highlighted throughout since it emphasizes the specific approaches taken by the bioengineering department at UIC.