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Plasma Medicine
SJR: 0.271 SNIP: 0.316 CiteScore™: 1.9

ISSN Imprimir: 1947-5764
ISSN En Línea: 1947-5772

Plasma Medicine

DOI: 10.1615/PlasmaMed.2016015838
pages 101-106

Interactions between a Plasma-Activated Medium and Cancer Cells

Hiromasa Tanaka
Plasma Nanotechnology Research Center, Nagoya University; Center for Advanced Medicine and Clinical Research, Nagoya University Graduate School of Medicine, Tsurumai-cho 65, Showa-ku, Nagoya 466-8550, Japan
Masaaki Mizuno
Center for Advanced Medicine and Clinical Research, Nagoya University Graduate School of Medicine, Tsurumai-cho 65, Showa-ku, Nagoya 466-8550, Japan
Fumitaka Kikkawa
Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine, Tsurumai-cho 65, Showa-ku, Nagoya 466-8550, Japan
Masaru Hori
Plasma Nanotechnology Research Center, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan

SINOPSIS

A plasma-activated medium (PAM) is a medium that is irradiated with plasma; PAMs have garnered much attention from the plasma medicine community. PAMs induce apoptosis in many types of cancer cells and have a clinical benefit, especially in disseminated cancers such as peritoneal disseminated ovarian cancer and gastric cancer. Although the effectiveness of PAMs has been extensively reported, the mechanisms of the selective killing of cancer cells by PAMs still remain to be elucidated. Systems biology is a key to understanding the origins of the differences in cellular sensitivities to PAM.


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