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Critical Reviews™ in Eukaryotic Gene Expression

Publicado 6 números por año

ISSN Imprimir: 1045-4403

ISSN En Línea: 2162-6502

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

Indexed in

Coordinated Regulation of Ras-, Rac-, and Ca2+-Dependent Signaling Pathways

Volumen 19, Edición 2, 2009, pp. 139-169
DOI: 10.1615/CritRevEukarGeneExpr.v19.i2.40
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SINOPSIS

Stimulation of cells by a broad variety of agonists results in a coordinated activation of Ca2+-, Ras-, and Rac-dependent pathways, which have to synergize to yield the corresponding biological response. This synergy requires a dense net of mutually positive and negative regulatory mechanisms. These include Ca2+-mediated activation of guanine nucleotide exchange proteins, resulting in increased levels of GTP-charged Ras and/or Rac or inactivation of small GTPases by Ca2+-mediated activation of GTPase-activating enzymes. Likewise, Ras as well as Rac control regulatory mechanisms, resulting in increased or diminished levels of cytosolic-free Ca2+. The biochemical mechanisms underlying these effects are discussed, with special reference to regulation of Ca2+ signaling by Ras and Rac.

CITADO POR
  1. Kim Bongju, Takeuchi Ayako, Hikida Masaki, Matsuoka Satoshi, Roles of the mitochondrial Na+-Ca2+ exchanger, NCLX, in B lymphocyte chemotaxis, Scientific Reports, 6, 1, 2016. Crossref

  2. Chang Fumin, Lemmon Christopher, Lietha Daniel, Eck Michael, Romer Lewis, Danen Erik H. J., Tyrosine Phosphorylation of Rac1: A Role in Regulation of Cell Spreading, PLoS ONE, 6, 12, 2011. Crossref

  3. Sasaki Shinya, Takeda Katsuhiro, Ouhara Kazuhisa, Shirawachi Satomi, Kajiya Mikihito, Matsuda Shinji, Kono Shoko, Shiba Hideki, Kurihara Hidemi, Mizuno Noriyoshi, Involvement of Rac1 in macrophage activation by brain-derived neurotrophic factor, Molecular Biology Reports, 48, 6, 2021. Crossref

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