Suscripción a Biblioteca: Guest
Portal Digitalde Biblioteca Digital eLibros Revistas Referencias y Libros de Ponencias Colecciones
Critical Reviews™ in Eukaryotic Gene Expression
Factor de Impacto: 1.841 Factor de Impacto de 5 años: 1.927 SJR: 0.649 SNIP: 0.516 CiteScore™: 1.96

ISSN Imprimir: 1045-4403
ISSN En Línea: 2162-6502

Volumes:
Volumen 30, 2020 Volumen 29, 2019 Volumen 28, 2018 Volumen 27, 2017 Volumen 26, 2016 Volumen 25, 2015 Volumen 24, 2014 Volumen 23, 2013 Volumen 22, 2012 Volumen 21, 2011 Volumen 20, 2010 Volumen 19, 2009 Volumen 18, 2008 Volumen 17, 2007 Volumen 16, 2006 Volumen 15, 2005 Volumen 14, 2004 Volumen 13, 2003 Volumen 12, 2002 Volumen 11, 2001 Volumen 10, 2000 Volumen 9, 1999 Volumen 8, 1998 Volumen 7, 1997 Volumen 6, 1996 Volumen 5, 1995 Volumen 4, 1994

Critical Reviews™ in Eukaryotic Gene Expression

DOI: 10.1615/CritRevEukaryotGeneExpr.v12.i1.10
22 pages

Coregulators of Estrogen Receptor Action

Gilles B. Tremblay
Drug Discovery Unit, SignalGene Inc., Montreal, PQ H2M 2N9, Canada
Vincent Giguere
Molecular Oncology Group, McGill University Health Center, Montreal, PQ H3A 1A1, Canada

SINOPSIS

The estrogen receptors are members of a large family of transcription factors, which include receptors for steroid hormones, retinoids, vitamin D and thyroid hormone, as well as several orphan receptors with yet undiscovered ligands. The process by which small lipophilic molecules signal in target tissues is complex and involves nuclear receptor associations with a multitude of coregulator proteins. These proteins participate in and recruit many enzymatic and structural activities that allow modulation of chromatin structure to facilitate stimulation or repression of gene expression. This review will present an overview of those regulatory factors that interact with the estrogen receptors and participate in the transmission of the estrogenic signal.