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Critical Reviews™ in Eukaryotic Gene Expression

Publicado 6 números por año

ISSN Imprimir: 1045-4403

ISSN En Línea: 2162-6502

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

Indexed in

The Effects of Heat-Shock on Nuclear Matrix-Associated DNA-Replication Complexes

Volumen 9, Edición 3-4, 1999, pp. 363-371
DOI: 10.1615/CritRevEukarGeneExpr.v9.i3-4.210
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SINOPSIS

To better understand the role of the nuclear matrix in heat-induced cell killing, we have investigated the effects of heat shock on DNA replication complexes. Changes in protein extractability are observed following heat shock, including stabilization of which stabilize DNA replication complexes in association with the nuclear matrix. This situation is accompanied by differential delays in the progress and completion of DNA synthesis and the transition from type I to type II DNA replication patterns. Interestingly, prolonged delays in restarting DNA synthesis produced significant protection from heat-induced cell killing. These results show that nuclear matrix-associated DNA replication complexes may be important targets for heat-induced cell killing.

CITADO POR
  1. Roti Roti J.L., Gius D., VanderWaal R.P., Xu M., Changes in sub-nuclear structures and functional perturbations: Implications for radiotherapy, Journal of Cellular Biochemistry, 79, S35, 2000. Crossref

  2. Agutter Paul S., Cell mechanics and stress: from molecular details to the ‘universal cell reaction’ and hormesis, BioEssays, 29, 4, 2007. Crossref

  3. Willsie Julia K., Clegg James S., Small heat shock protein p26 associates with nuclear lamins and HSP70 in nuclei and nuclear matrix fractions from stressed cells, Journal of Cellular Biochemistry, 84, 3, 2002. Crossref

  4. Roti Roti Joseph L., Cellular responses to hyperthermia (40–46°C): Cell killing and molecular events, International Journal of Hyperthermia, 24, 1, 2008. Crossref

  5. Roti Roti Joseph L., Heat-induced alterations of nuclear protein associations and their effects on DNA repair and replication, International Journal of Hyperthermia, 23, 1, 2007. Crossref

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