Suscripción a Biblioteca: Guest
Portal Digitalde Biblioteca Digital eLibros Revistas Referencias y Libros de Ponencias Colecciones
International Journal of Medicinal Mushrooms
Factor de Impacto: 1.423 Factor de Impacto de 5 años: 1.525 SJR: 0.431 SNIP: 0.661 CiteScore™: 1.38

ISSN Imprimir: 1521-9437
ISSN En Línea: 1940-4344

Volumes:
Volumen 21, 2019 Volumen 20, 2018 Volumen 19, 2017 Volumen 18, 2016 Volumen 17, 2015 Volumen 16, 2014 Volumen 15, 2013 Volumen 14, 2012 Volumen 13, 2011 Volumen 12, 2010 Volumen 11, 2009 Volumen 10, 2008 Volumen 9, 2007 Volumen 8, 2006 Volumen 7, 2005 Volumen 6, 2004 Volumen 5, 2003 Volumen 4, 2002 Volumen 3, 2001 Volumen 2, 2000 Volumen 1, 1999

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushrooms.v7.i3.360
pages 386-387

Medically Significant White-Rot Basidiomycetes: Metabolic and Biochemical Characteristics

Nina V. Belova
Laboratory of Biochemistry of the Fungi of the Komarov Botanical Institute of the Russian Academy of Sciences, St. Petersburg, Russia
Natalia S. Yakovleva
Komarov Botanical Institute, Russian Academy of Sciences, 2 Popova ul., St. Petersburg 197376, Russia

SINOPSIS

Cultural investigations of white-rot fungi began in the middle of the 20th century due to identification of their capabilities to grow on different nutrient substrates and to exist for long periods in the mycelium stage. This peculiarity of white-rot fungi makes possible their conservation ex situ in culture collections. The ability of basidiome formation during cultivation permits use of some edible white-rot Basidiomycetes for fruit body production, identification, and verification of strains during experimental conditions. The high enzymatic potential of white-rot fungi and their ability to grow in and on substrates permits their use in various types of wastes.
Physiological investigations of white-rot fungi established different peculiarities of the second metabolism of this fungi group. It was shown that many low-molecular weight compounds isolated from white-rot Basidiomycetes determine their flavor, pigmentation, and biological activities. The properties, structures, and characteristics of activities of many terpenoid, alkaloid, phenylquinoid, and anthraquinoid metabolites were established. At present some mushrooms produce substances used in aromatherapy and in the preparation of sanative beverages (i.e., Marasmius sp., Gloeophyllum odoratum (Wulfen) Imazeki, Lentinus edodes). Others are used in the preparation of medicinal drugs containing mucidin, inotodiol, and ganodermanes (i.e., Oudemansiella mucida (Schrad.) Hohn., Inonotus obliquus (Ach. ex Pers.) Pilat, Ganoderma lucidum). High-molecular weight substances such as polysaccharides are also the products of the second metabolism of white-rot basidiomycetes. Today, polysaccharides are the main constituents of some drugs and dietary supplements well known in countries of the southeast regions on Earth. These medicinal products are obtained by fermentation—white-rot Basidiomycetes such as Lentinus edodes, Trametes sp., Schizophyllum commune Fr.:Fr., and some others.
Investigations of the hydrolytic enzymes of white-rot fungi allow indicating the presence of different types of proteases and obtaining the secreted fibrinolytic proteases from Flammulina and Coprinus species and milk clothing enzymes from Mycena pura (Pers.:Fr.) P. Kumm., Irpex lacteus (Fr.) Fr., and Sparassis crispa (Wulfen) Fr. In the last three decades, the enzymatic activity of white-rot Basidiomycetes has been causing great interest, resulting in active investigations. It was shown that among Gem-, Flavin-, and Cu-containing oxidases produced by these fungi, the main role in degrading lignin belonged to lignin peroxidases, manganese peroxidases, and laccases. Biochemical investigations of some species from families Polyporaceae, Ganodermataceae, and Strophariaceae have shown that these white-rot Basidiomycetes produce different oxidases, among which laccases were the main enzymes. Some characteristics of isolated laccases were investigated in cooperation with colleagues from the Bach Biochemistry Institute RAS. Great interest in the practical use of oxidative enzymes of Basidiomycetes is explained in their chemical and catalytic features. The possibility of oxidation of different aromatic, principally phenolic substances to quinones is now very well known in different areas of industry and medicine.


Articles with similar content:

The Influence of the Cultivation Conditions on the Chemical Composition of Medicinal Mushrooms Pleurotus ostreatus (Jacq.: Fr.) Kumm. and Lentinus edodes (Berk.) Sing.
International Journal of Medicinal Mushrooms, Vol.1, 1999, issue 2
Valentina G. Babitskaya, Victor V. Scherba, Valentina I. Fomina, Vycheslav V. Truchonovec, Nina A. Bisko, Nadezda Yu. Mitropolskaya
Biotechnological Potential of Mushrooms: Drugs and Dye Production
International Journal of Medicinal Mushrooms, Vol.8, 2006, issue 4
Girish Tidke, Mahendra K. Rai
Mycoremediation: Current State and Perspectives
International Journal of Medicinal Mushrooms, Vol.7, 2005, issue 3
Tomas Cajthaml, Vaclav Sasek
Role of Women in Mushroom Cultivation: Indian Perspectives
International Journal of Medicinal Mushrooms, Vol.7, 2005, issue 3
Mahendra K. Rai, Alka S. Karwa
Fatty Acid Composition of Different Collections of Coprinoid Mushrooms (Agaricomycetes) and Their Nutritional and Medicinal Values
International Journal of Medicinal Mushrooms, Vol.18, 2016, issue 10
Susanna M. Badalyan