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International Journal of Medicinal Mushrooms

Publicado 12 números por año

ISSN Imprimir: 1521-9437

ISSN En Línea: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Simple and Reproducible Two-Stage Agitation Speed Control Strategy for Enhanced Triterpene Production by Lingzhi or Reishi Medicinal Mushrooms, Ganoderma lucidum ACCC G0119 (Higher Basidiomycetes) Based on Submerged Liquid Fermentation

Volumen 17, Edición 12, 2015, pp. 1151-1159
DOI: 10.1615/IntJMedMushrooms.v17.i12.50
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SINOPSIS

Triterpenes are important anticancer agents produced by batch submerged liquid fermentation, with the medicinal mushroom Ganoderma lucidum ACCC G0119, which was investigated under various dissolved oxygen levels by varying agitation speeds. Three kinetic parameters were analyzed: specific mycelial growth rate (μsmg), specific glucose consumption rate (qsgc), and specific triterpene production rate (qstp). High concentration, yield, and productivity of triterpenes were achieved by developing a simple and reproducible two-stage agitation speed control strategy. At the first 40 h, agitation speed was controlled at 150 rpm to obtain the quickest peak qstp for triterpene production, subsequently agitation speed was controlled at 100 rpm to maintain high qstp for high triterpene accumulation. The maximum concentration of triterpenes reached 0.086 g/l with the yield of 6.072 g/kg and the productivity of 6.532 × 10−4 g/(l·h), which were 39.61%, 36.48%, and 49.22%, respectively, better than the best results controlled by fixed agitation speeds. Conceivably, such a triterpene fermentation production strategy would be useful for industrial large-scale production of triterpenes with G. lucidum.

CITADO POR
  1. Feng Jie, Feng Na, Zhang Jing-Song, Yang Yan, Jia Wei, Lin Chi-Chung, A New Temperature Control Shifting Strategy for Enhanced Triterpene Production by Ganoderma lucidum G0119 Based on Submerged Liquid Fermentation, Applied Biochemistry and Biotechnology, 180, 4, 2016. Crossref

  2. Sun Ling, Liu Liping, Yang Lei, Wang Yazhen, Dabbour Mokhtar, Mintah Benjamin Kumah, He Ronghai, Ma Haile, Effects of low‐intensity ultrasound on the biomass and metabolite of Ganoderma lucidum in liquid fermentation , Journal of Food Process Engineering, 44, 1, 2021. Crossref

  3. Lu Hongyun, Lou Hanghang, Hu Jingjin, Liu Zhengjie, Chen Qihe, Macrofungi: A review of cultivation strategies, bioactivity, and application of mushrooms, Comprehensive Reviews in Food Science and Food Safety, 19, 5, 2020. Crossref

  4. Liu Ting-Ting, Zhong Jian-Jiang, Impact of oxygen supply on production of a novel ganoderic acid in Saccharomyces cerevisiae fermentation, Process Biochemistry, 106, 2021. Crossref

  5. Liu Ting-Ting, Xiao Han, Xiao Jian-Hui, Zhong Jian-Jiang, Impact of oxygen supply on production of terpenoids by microorganisms: State of the art, Chinese Journal of Chemical Engineering, 30, 2021. Crossref

  6. Hanafiah Z. M., Wan Mohtar W. H. M., Hasan H. A., Jensen H. S., Klaus A., Sharil S., Wan-Mohtar W. A. A. Q. I., Ability of Ganoderma lucidum mycelial pellets to remove ammonia and organic matter from domestic wastewater, International Journal of Environmental Science and Technology, 19, 8, 2022. Crossref

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