Publicado 12 números por año
ISSN Imprimir: 1521-9437
ISSN En Línea: 1940-4344
Indexed in
Purification of Caffeic Acid as an Antioxidant from Submerged Culture Mycelia of Phellinus linteus (Berk. et Curt.) Teng (Aphyllophoromycetideae)
SINOPSIS
Phellinus linteus mycelia have many pharmacological effects although their pharmacological efficacy principles have not been known before. In the course of screening for biological activity of the extracts of Ph. Linteus mycelia, we found strong antioxidative activity in the extract. Therefore, we tried to isolate the active principle(s) from the extract. The isolation of the active compound was guided by superoxide anion radical scavenging activity. As a result, caffeic acid was isolated as an active compound. The IC50 of the compound was 3.05 μg/mL (16.9 μM).
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