Suscripción a Biblioteca: Guest
Portal Digitalde Biblioteca Digital eLibros Revistas Referencias y Libros de Ponencias Colecciones
International Journal of Medicinal Mushrooms
Factor de Impacto: 1.423 Factor de Impacto de 5 años: 1.525 SJR: 0.431 SNIP: 0.661 CiteScore™: 1.38

ISSN Imprimir: 1521-9437
ISSN En Línea: 1940-4344

Volumes:
Volumen 21, 2019 Volumen 20, 2018 Volumen 19, 2017 Volumen 18, 2016 Volumen 17, 2015 Volumen 16, 2014 Volumen 15, 2013 Volumen 14, 2012 Volumen 13, 2011 Volumen 12, 2010 Volumen 11, 2009 Volumen 10, 2008 Volumen 9, 2007 Volumen 8, 2006 Volumen 7, 2005 Volumen 6, 2004 Volumen 5, 2003 Volumen 4, 2002 Volumen 3, 2001 Volumen 2, 2000 Volumen 1, 1999

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushr.v14.i6.30
pages 557-561

The Protective Effects of Aqueous Extracts of Wild-Growing and Fermented Royal Sun Mushroom, Agaricus brasiliensis S. Wasser et al. (Higher Basidiomycetes), in CCl4-Induced Oxidative Damage in Rats

Chunjing Zhang
Department of Biochemistry and Molecular Biology, Qiqihar Medical University, Qiqihar Heilongjiang, PR China
Chunchao Han
School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, People's Republic of China
Baosheng Zhao
Center of Scientific Experiment, Beijing University of Chinese Medicine, Beijing 100029, P.R. China
Haitao Yu
Department of Biochemistry and Molecular Biology, Harbin Medical University, Heilongjiang Harbin; Department of Biology Genetics, Qiqihar Medical University, Qiqihar Heilongjiang, PR China

SINOPSIS

Culinary-medicinal Royal Sun mushroom, Agaricus brasiliensis (AbS), has traditionally been used for the prevention of a range of diseases, including cancer, hepatitis, atherosclerosis, hypercholesterolemia, diabetes, and dermatitis. The hepatoprotective effect of the fermented mushroom of A. brasiliensis (FMAE) and wild-growing A. brasiliensis (WMAE) were studied in this paper. An in vivo study of carbon tetrachloride (CCl4)-induced antioxidant activity in 2-month-old rats was conducted by examining the levels of activities of alanine aminotransaminase (ALT) and aspartate aminotransaminase (AST) and the antioxidant enzymes, including glutathione peroxidase (GSHPx) and catalase (CAT). Rats were divided into four groups, each containing six rats. The first group served as a control group. The second group was the CCl4 group. Group I and group II were treated orally with distilled water for 14 days respectively. Group III and Group IV were treated orally by WMAE and FMAE at oral doses of 50 mg/kg-day, respectively. Both WMAE and FMAE could reduce CCl4-induced toxicity, particularly hepatotoxicity, by suppressing ALT and AST activities, and increasing antioxidant enzyme activity. The studies demonstrate that both the fermented and wild-growing A. brasiliensis could protect the liver against CCl4-induced oxidative damage in rats.


Articles with similar content:

Hepatoprotective and Immunosuppressive Effect of Synedrella nodiflora L. on Carbon Tetrachloride (CCl4)-Intoxicated Rats
Journal of Environmental Pathology, Toxicology and Oncology, Vol.35, 2016, issue 1
Muhammad Dawood Shah, A.T.M. Emdadul Haque, Mohammad Iqbal, Jaafar Sadeq Makki, Charles Gnanaraj
Protective Effects of Extract from Sclerotium of the King Tuber Medicinal Mushroom, Pleurotus tuberregium (Higher Basidiomycetes) on Carbon Tetrachloride-Induced Hepatotoxicity in Wistar Albino Rats
International Journal of Medicinal Mushrooms, Vol.17, 2015, issue 12
Christopher C. Osubor, Chidube A. Alagbaoso, Omoanghe S. Isikhuemhen
Effects of Total Triterpenoids Extract from Ganoderma Iucidum (Curt.: Fr.) P. Karst. (Reishi Mushroom) on Experimental Liver Injury Models Induced by Carbon Tetrachloride or D-Galactosamine in Mice
International Journal of Medicinal Mushrooms, Vol.4, 2002, issue 4
Ming-Yu Wang, Qing-Ming Che, Qiang Liu, Zhi-Bin Lin
Hepato- and Nephroprotective Activities of a Nigerian Local King Tuber Oyster Mushroom, Pleurotus tuberregium (Higher Basidiomycetes), in Chemically Induced Organ Toxicities in Rats
International Journal of Medicinal Mushrooms, Vol.16, 2014, issue 4
Stella A. Ihim, Kolawole A. Laiyemo, Chukwuemeka Sylvester Nworu, Peter A. Akah, Loveth E. Ugwu
Modulatory Effect of Crude Aqueous Extract of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Higher Basidiomycetes), on Hematological and Antioxidant Indices in Plasmodium berghei−infected Mice
International Journal of Medicinal Mushrooms, Vol.16, 2014, issue 5
Olarewaju M. Oluba, Kayode E. Adebisi, E. Chukwu Onyeneke, Adewale A. Odutuga, George O. Eidangbe