Suscripción a Biblioteca: Guest
Portal Digitalde Biblioteca Digital eLibros Revistas Referencias y Libros de Ponencias Colecciones
International Journal of Medicinal Mushrooms
Factor de Impacto: 1.423 Factor de Impacto de 5 años: 1.525 SJR: 0.431 SNIP: 0.661 CiteScore™: 1.38

ISSN Imprimir: 1521-9437
ISSN En Línea: 1940-4344

Volumes:
Volumen 21, 2019 Volumen 20, 2018 Volumen 19, 2017 Volumen 18, 2016 Volumen 17, 2015 Volumen 16, 2014 Volumen 15, 2013 Volumen 14, 2012 Volumen 13, 2011 Volumen 12, 2010 Volumen 11, 2009 Volumen 10, 2008 Volumen 9, 2007 Volumen 8, 2006 Volumen 7, 2005 Volumen 6, 2004 Volumen 5, 2003 Volumen 4, 2002 Volumen 3, 2001 Volumen 2, 2000 Volumen 1, 1999

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushrooms.2017021151
pages 641-651

Optimization of Submerged Cultivation Conditions for Production of Big Cup Culinary-Medicinal Mushroom Clitocybe maxima (Agaricomycetes) Biomass with Significant Antioxidative and Antihyperlipidemic Activities

Shu-Hui Hu
Department of Nutrition and Dietetics, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan; Department of Medical Laboratory Science and Biotechnology, Kaohsiung Medical University, Kaohsiung, Taiwan
Ker-Shew Chen
Department of Pharmacy, Tajen University, Pingtung, Taiwan
Ming-Yi Liu
Department of Dietetics, Tainan Sin-Lau Hospital, Tainan, Taiwan
Peter Chi Keung Cheung
School of Life Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China
Jinn-Chyi Wang
Department of Food Science and Technology, Tajen University, Pingtung, Taiwan
Sue-Joan Chang
Department of Life Science, National Cheng Kung University, Tainan, Taiwan, 701

SINOPSIS

In this study, a large Clitocybe maxima mycelium biomass was obtained by submerged cultivation under optimal conditions. Three test samples from lyophilized mycelia, including hot water extract (CW) and elutes from solvents with different polarity (CA and CB), were combined and used to explore antioxidant and antihyper-lipidemic activities in vitro and in vivo. The CA group showed the highest DPPH free radical scavenging activity and iron-reducing capability at concentrations of 6.0% and 3.0% (w/v), respectively. Further, the CA group showed the highest glutathione peroxidase and superoxide dismutase activities at a dose of 0.25 mg/kg body weight (CA-0.25 group) in all hyperlipidemic hamsters tested. Serum lipid levels (apart from high-density lipoprotein cholesterol levels) of hamsters in the CA-0.25 group were lower than those of hamsters in the negative control group in antihy-perlipidemic tests. Therefore, we believe that extracts from C. maxima mycelia are rich reservoirs of antioxidant and antihyperlipidemic activities.


Articles with similar content:

Modulatory Effect of Crude Aqueous Extract of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Higher Basidiomycetes), on Hematological and Antioxidant Indices in Plasmodium berghei−infected Mice
International Journal of Medicinal Mushrooms, Vol.16, 2014, issue 5
Olarewaju M. Oluba, Kayode E. Adebisi, E. Chukwu Onyeneke, Adewale A. Odutuga, George O. Eidangbe
Protective Effects of Extract from Sclerotium of the King Tuber Medicinal Mushroom, Pleurotus tuberregium (Higher Basidiomycetes) on Carbon Tetrachloride-Induced Hepatotoxicity in Wistar Albino Rats
International Journal of Medicinal Mushrooms, Vol.17, 2015, issue 12
Christopher C. Osubor, Chidube A. Alagbaoso, Omoanghe S. Isikhuemhen
Evaluation and Characterization of Nutritive Properties of the Jelly Ear Culinary-Medicinal Mushroom Auricularia auricula-judae (Agaricomycetes) from Nigeria
International Journal of Medicinal Mushrooms, Vol.19, 2017, issue 2
Reginald Chibueze Ohiri, Essien Eka Bassey
Determination of the Antioxidant Activity and Polyphenol Contents of Wild Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (W.Curt. Fr.) P. Karst. (Higher Basidiomycetes) from Central Himalayan Hills of India
International Journal of Medicinal Mushrooms, Vol.13, 2011, issue 6
Prem Singh Negi, Zakwan Ahmed, Mohammed Mohsin
Ethanolic Extract of the Golden Oyster Mushroom, Pleurotus citrinopileatus (Agaricomycetes), Alleviates Metabolic Syndrome in Diet-Induced Obese Mice
International Journal of Medicinal Mushrooms, Vol.19, 2017, issue 11
Changhui Zhao, Quanbo Chi, Kunlun Huang, Pengfei Shi, Guoyi Wang, Yao Sheng, Wentao Xu