Suscripción a Biblioteca: Guest
International Journal of Medicinal Mushrooms

Publicado 12 números por año

ISSN Imprimir: 1521-9437

ISSN En Línea: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

Indexed in

Extracellular Polysaccharopeptides from Fermented Turkey Tail Medicinal Mushroom, Trametes versicolor (Agaricomycetes), Mitigate Oxidative Stress, Hyperglycemia, and Hyperlipidemia in Rats with Type 2 Diabetes Mellitus

Volumen 22, Edición 5, 2020, pp. 417-429
DOI: 10.1615/IntJMedMushrooms.2020034560
Get accessGet access

SINOPSIS

The antihyperglycemic activity of extracellular polysaccharopeptides (ePSP) obtained from Trametes versicolor (TV) strain LH-1 has been reported to increase cellular glucose uptake in HepG2 cells in an insulin-independent manner. Evidence indicates that oxidative stress plays a pivotal role in the development of diabetic complications. We aimed to use an in vivo model to investigate the effects of TV-ePSP on oxidative stress and glucose homeostasis in type 2 diabetes mellitus (T2DM). Male Wistar rats fed with a high fat diet followed by a streptozotocin injection to induce T2DM were orally administered water or 0.1, 0.5, or 1.0 g/kg of TV-ePSP per day. After a 4-week administration of TV-ePSP, T2DM rats had attenuated elevations in blood glucose levels, areas under the curve in oral glucose tolerance tests, insulin resistance indices, and serum fructosamine and triglyceride in a dose-dependent manner (P < 0.05, one-way ANOVA). In addition, TV-ePSP significantly alleviated oxidative stress in T2DM rats, as shown by the decreased lipid peroxidation and the increased activity of superoxide dismutase in the plasma, and by the elevated glutathione levels in the plasma and erythrocytes. The antihyperglycemia and antihypertriglyceridemia activities of TV-ePSP may be associated with the improved oxidative stress, suggesting the beneficial effects of TV-ePSP in preventing the development of diabetic complications in T2DM patients.

REFERENCIAS
  1. Cho NH, Shaw JE, Karuranga S, Huang Y, da Rocha Fernandes JD, Ohlrogge AW, Malanda B. IDF Diabetes Atlas: Global estimates of diabetes prevalence for 2017 and projections for 2045. Diabetes Res Clin Pract. 2018;138:271-81.

  2. Nwose EU, Richards RS, Digban K, Bwititi PT, Ennis G, Yee KC, Oguoma VM, Liberato S. Cardiovascular risk assessment in prediabetes and undiagnosed diabetes mellitus study: International collaboration research overview. N Am J Med Sci. 2013;5:625-30.

  3. Dobrian AD, Davies MJ, Schriver SD, Lauterio TJ, Prewitt RL. Oxidative stress in a rat model of obesity-induced hypertension. Hypertension. 2001;37:554-60.

  4. Tangvarasittichai S. Oxidative stress, insulin resistance, dyslipidemia and type 2 diabetes mellitus. World J Diabetes. 2015;6:456-80.

  5. Jayakumar P, Pugalendi KV, Sankaran M. Attenuation of hyperglycemia-mediated oxidative stress by indole-3-carbinol and its metabolite 3,3'-diindolylmethane in C57BL/6J mice. J Physiol Biochem. 2014;70:525-34.

  6. Quatrin A, Conte L, da Silva DT, Figueiredo CG, Somacal S, Roehrs M, Teixeira CF, Barbisan F, Augusti PR, Marostica Junior MR, da Cruz IBM, Emanuelli T. The hepatoprotective effect of Jaboticaba peel powder in a rat model of type 2 diabetes mellitus involves the modulation of thiol/disulfide Redox state through the upregulation of glutathione synthesis. J Nutr Metab. 2018;2018:9794629.

  7. Morsi HK, Ismail MM, Gaber HA, Elbasmy AA. Macrophage migration inhibitory factor and malondialdehyde as potential predictors of vascular risk complications in type 2 diabetes mellitus: Cross-sectional case control study in Saudi Arabia. Mediators Inflamm. 2016;2016:5797930.

  8. Cui J, Goh KK, Archer R, Singh H. Characterisation and bioactivity of protein-bound polysaccharides from submerged-culture fermentation of Coriolus versicolor Wr-74 and ATCC-20545 strains. J Ind Microbiol Biotechnol. 2007;34:393-402.

  9. Chen J, Jin X, Zhang L, Yang L. A study on the antioxidant effect of Coriolus versicolor polysaccharide in rat brain tissues. Afr J Tradit Complement Altern Med. 2013;10:481-4.

  10. Liu M, Song X, Zhang J, Zhang C, Gao Z, Li S, Jing H, Ren Z, Wang S, Jia L. Protective effects on liver, kidney and pancreas of enzymatic- and acidic-hydrolysis of polysaccharides by spent mushroom compost (Hypsizygus marmoreus). Sci Rep. 2017;7:43212.

  11. Vitak TY, Wasser SP, Nevo E, Sybirna NO. Enzymatic system of antioxidant protection of erythrocytes in diabetic rats treated with medicinal mushrooms Agaricus brasiliensis and Ganoderma lucidum (Agaricomycetes). Int J Med Mushrooms. 2017;19:697-708.

  12. Wang J, Wang C, Li S, Li W, Yuan G, Pan Y, Chen H. Anti-diabetic effects of Inonotus obliquus polysaccharides in streptozotocin-induced type 2 diabetic mice and potential mechanism via PI3K-Akt signal pathway. Biomed Pharmacother. 2017;95:1669-77.

  13. Liu M, Lan Y, Tian C, Zhu Y, Liu H, Wang W, Liu W, Zhang J, Jia L. The characterization, renoprotection and antioxidation of enzymatic and acidic exopolysaccharides from Hypsizygus marmoreus. Sci Rep. 2018;8:2048.

  14. Teng JF, Lee CH, Hsu TH, Lo HC. Potential activities and mechanisms of extracellular polysaccharopeptides from fermented Trametes versicolor on regulating glucose homeostasis in insulin-resistant HepG2 cells. PLoS One. 2018;13:e0201131.

  15. Kou L, Du M, Liu P, Zhang B, Zhang Y, Yang P, Shang M, Wang X. Anti-diabetic and anti-nephritic activities of Grifola frondosa mycelium polysaccharides in diet-streptozotocin-induced diabetic rats via modulation on oxidative stress. Appl Biochem Biotechnol. 2019;187:310-22.

  16. Lin FY, Lai YK, Yu HC, Chen NY, Chang CY, Lo HC, Hsu TH. Effects of Lycium barbarum extract on production and immunomodulatory activity of the extracellular polysaccharopeptides from submerged fermentation culture of Coriolus versicolor. Food Chem. 2008;110:446-53.

  17. Jimenez-Medina E, Berruguilla E, Romero I, Algarra I, Collado A, Garrido F, Garcia-Lora A. The immunomodulator PSK induces in vitro cytotoxic activity in tumour cell lines via arrest of cell cycle and induction of apoptosis. BMC Cancer. 2008;8:78.

  18. Wang Z, Dong B, Feng Z, Yu S, Bao Y. A study on immunomodulatory mechanism of polysaccharopeptide mediated by TLR4 signaling pathway. BMC Immunol. 2015;16:34.

  19. Lai CH, Teng JF, Hsu TH, Lin FY, Yang PW, Lo HC. 28-day oral safety evaluation of extracellular polysaccharopeptides produced in submerged culture from the turkey tail medicinal mushroom Trametes versicolor (L.:Fr.) Pilat LH-1 in mice. Int J Med Mushrooms. 2011;13:227-36.

  20. Yang JP, Hsu T, Lin F, Hsu W, Chen Y. Potential antidiabetic activity of extracellular polysaccharides in submerged fermentation culture of Coriolus versicolor LH1. Carbohydr Polym. 2012;90:174-80.

  21. Chen CH, Kang L, Lo HC, Hsu TH, Lin FY, Lin YS, Wang ZJ, Chen ST, Shen CL. Polysaccharides of Trametes versicolor improve bone properties in diabetic rats. J Agric Food Chem. 2015;63:9232-8.

  22. Lo HC, Tsai FA, Wasser SP, Yang JG, Huang BM. Effects of ingested fruiting bodies, submerged culture biomass, and acidic polysaccharide glucuronoxylomannan of Tremella mesenterica Retz.:Fr. on glycemic responses in normal and diabetic rats. Life Sci. 2006;78:1957-66.

  23. Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem. 1979;95:351-8.

  24. Sedlak J, Lindsay RH. Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent. Anal Biochem. 1968;25:192-205.

  25. Hissin PJ, Hilf R. A fluorometric method for determination of oxidized and reduced glutathione in tissues. Anal Biochem. 1976;74:214-26.

  26. Marklund S, Marklund G. Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem. 1974;47:469-74.

  27. Awasthi YC, Beutler E, Srivastava SK. Purification and properties of human erythrocyte glutathione peroxidase. J Biol Chem. 1975;250:5144-9.

  28. Aebi H. Catalase in vitro. Methods Enzymol. 1984;105:121-6.

  29. Hartz JC, de Ferranti S, Gidding S. Hypertriglyceridemia in diabetes mellitus: Implications for pediatric care. J Endocr Soc. 2018;2:497-512.

  30. Asmat U, Abad K, Ismail K. Diabetes mellitus and oxidative stress-A concise review. Saudi Pharm J. 2016;24:547-53.

  31. Xuan Y, Gao X, Anusruti A, Holleczek B, Jansen E, Muhlack DC, Brenner H, Schottker B. Association of serum markers of oxidative stress with incident major cardiovascular events, cancer incidence and all-cause mortality in type 2 diabetes patients: Pooled results from two cohort studies. Diabetes Care. 2019;42(8):1436-1445.

  32. Wu T, Xu B. Antidiabetic and antioxidant activities of eight medicinal mushroom species from China. Int J Med Mushrooms. 2015;17:129-40.

  33. Mihailovic M, Arambasic JJ, Uskokovic A, Grdovic N, Dinic S, Vidovic S, Poznanovic G, Mujic I, Vidakovic M. Protective effects of the mushroom Lactarius deterrimus extract on systemic oxidative stress and pancreatic islets in streptozotocin-induced diabetic rats. J Diabetes Res. 2015;2015:576726.

  34. Rony KA, Ajith TA, Janardhanan KK. Hypoglycemic and hypolipidemic effects of the cracked-cap medicinal mushroom Phellinus rimosus (higher Basidiomycetes) in streptozotocin-induced diabetic rats. Int J Med Mushrooms. 2015;17:521-31.

  35. Subramaniam S, Raman J, Sabaratnam V, Heng CK, Kuppusamy UR. Functional properties of partially characterized polysaccharide from the medicinal mushroom Ganoderma neo-japonicum (Agaricomycetes). Int J Med Mushrooms. 2017;19:849-59.

  36. Nyam KL, Chow CF, Tan CS, Ng ST. Antidiabetic properties of the tiger's milk medicinal mushroom, Lignosus rhinocerotis (Agaricomycetes), in streptozotocin-induced diabetic rats. Int J Med Mushrooms. 2017;19:607-17.

  37. Grotto D, Bueno DC, Ramos GK, da Costa SR, Spim SR, Gerenutti M. Assessment of the safety of the shiitake culinary-medicinal mushroom, Lentinus edodes (Agaricomycetes), in rats: Biochemical, hematological, and antioxidative parameters. Int J Med Mushrooms. 2016;18:861-70.

  38. Pandey KB, Rizvi SI. Markers of oxidative stress in erythrocytes and plasma during aging in humans. Oxid Med Cell Longev. 2010;3:2-12.

  39. Marrocco I, Altieri F, Peluso I. Measurement and clinical significance of biomarkers of oxidative stress in humans. Oxid Med Cell Longev. 2017;2017:6501046.

  40. Yuan T, Yang T, Chen H, Fu D, Hu Y, Wang J, Yuan Q, Yu H, Xu W, Xie X. New insights into oxidative stress and inflammation during diabetes mellitus-accelerated atherosclerosis. Redox Biol. 2019;20:247.

CITADO POR
  1. Dare Ayobami, Channa Mahendra L., Nadar Anand, L-ergothioneine and metformin alleviates liver injury in experimental type-2 diabetic rats via reduction of oxidative stress, inflammation, and hypertriglyceridemia, Canadian Journal of Physiology and Pharmacology, 99, 11, 2021. Crossref

  2. Zhang Jing-Yao, Lo Hui-Chen, Yang Feili Lo, Liu Yi-Fang, Wu Wen-Mein, Chou Chi-Chun, Plant-Based, Antioxidant-Rich Snacks Elevate Plasma Antioxidant Ability and Alter Gut Bacterial Composition in Older Adults, Nutrients, 13, 11, 2021. Crossref

  3. Nazir Nausheen, Zahoor Muhammad, Nisar Mohammad, Khan Imran, Ullah Riaz, Alotaibi Amal, Antioxidants Isolated from Elaeagnus umbellata (Thunb.) Protect against Bacterial Infections and Diabetes in Streptozotocin-Induced Diabetic Rat Model, Molecules, 26, 15, 2021. Crossref

  4. Yang Xiaoqian, Lin Ping, Wang Jin, Liu Na, Yin Fan, Shen Nuo, Guo Shoudong, Purification, characterization and anti-atherosclerotic effects of the polysaccharides from the fruiting body of Cordyceps militaris, International Journal of Biological Macromolecules, 181, 2021. Crossref

  5. Wu Wen-Tzu, Hsu Tai-Hao, Chen Woan-Ling, Yang Chueh-Ko, Lo Hui-Chen, Polysaccharides of Grifola frondosa ameliorate oxidative stress and hypercholesterolaemia in hamsters fed a high-fat, high-cholesterol diet, Journal of Pharmacy and Pharmacology, 74, 9, 2022. Crossref

7040 Vistas de artículos 39 Descargas de artículos Métrica
7040 PUNTOS DE VISTA 39 DESCARGAS 5 Crossref CITAS Google
Scholar
CITAS

Artículos con contenido similar:

The Medicinal Cracked-Cap Polypore Mushroom Phellinus rimosus (Higher Basidiomycetes) Attenuates Alloxan-Induced Hyperglycemia and Oxidative Stress in Rats International Journal of Medicinal Mushrooms, Vol.15, 2013, issue 3
Thekkuttuparambil Ananthanarayanan Ajith, Kainoor Krishnankutty Janardhanan, Kuttikkadan A. Rony, John Mathew
The Effect of the Medicinal Mushrooms Agaricus brasiliensis and Ganoderma lucidum (Higher Basidiomycetes) on the Erythron System in Normal and Streptozotocin-Induced Diabetic Rats International Journal of Medicinal Mushrooms, Vol.17, 2015, issue 3
Solomon P. Wasser, Nataliya O. Sybirna, Taras Y. Vitak, Eviatar D. Nevo
Hypoglycemic and Hypolipidemic Effects of the Cracked-Cap Medicinal Mushroom Phellinus rimosus (Higher Basidiomycetes) in Streptozotocin-Induced Diabetic Rats International Journal of Medicinal Mushrooms, Vol.17, 2015, issue 6
Thekkuttuparambil Ananthanarayanan Ajith, Kainoor Krishnankutty Janardhanan, Kuttikkadan A. Rony
Endothelial Monocyte Activating Peptide II: Serum Levels in Type 1 Diabetes Mellitus International Journal of Physiology and Pathophysiology, Vol.8, 2017, issue 1
Liliya A. Mogylnytska, Olesya E. Mogylnytska
Renoprotective Effects of Shout Camphor Medicinal Mushroom (Taiwanofungus camphorates, Basidiomycetes) Mycelia on Several Media in Mice with Chronic Kidney Disease International Journal of Medicinal Mushrooms, Vol.18, 2016, issue 12
Shu-Chi Wang, Alexandru Mihai Grumezescu, Yu-Mei Lin, Hsin-Yi Su, Cing-Yan Jhang, Chih-Hui Yang, Keng-Shiang Huang, Jiun-Hua Chou, Ruo-Yun Chung, Wei-Ting Wang
Portal Digitalde Biblioteca Digital eLibros Revistas Referencias y Libros de Ponencias Colecciones Precios y Políticas de Suscripcione Begell House Contáctenos Language English 中文 Русский Português German French Spain