Suscripción a Biblioteca: Guest
Portal Digitalde Biblioteca Digital eLibros Revistas Referencias y Libros de Ponencias Colecciones
International Journal of Medicinal Mushrooms
Factor de Impacto: 1.423 Factor de Impacto de 5 años: 1.525 SJR: 0.431 SNIP: 0.661 CiteScore™: 1.38

ISSN Imprimir: 1521-9437
ISSN En Línea: 1940-4344

Volumes:
Volumen 21, 2019 Volumen 20, 2018 Volumen 19, 2017 Volumen 18, 2016 Volumen 17, 2015 Volumen 16, 2014 Volumen 15, 2013 Volumen 14, 2012 Volumen 13, 2011 Volumen 12, 2010 Volumen 11, 2009 Volumen 10, 2008 Volumen 9, 2007 Volumen 8, 2006 Volumen 7, 2005 Volumen 6, 2004 Volumen 5, 2003 Volumen 4, 2002 Volumen 3, 2001 Volumen 2, 2000 Volumen 1, 1999

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushrooms.v18.i12.10
pages 1061-1069

Genoprotective Capacity of Alternatively Cultivated Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Basidiocarps

Jasmina Ćilerdžić
Institute of Botany and Botanical Garden "Jevremovac", Faculty of Biology, University of Belgrade, Takovska 43, 11000 Belgrade, Serbia
Mirjana Stajic
Institute of Botany and Botanical Garden "Jevremovac", Faculty of Biology, University of Belgrade, Takovska 43, 11000 Belgrade, Serbia
Lada Živković
Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia
Jelena Vukojević
Institute of Botany and Botanical Garden "Jevremovac", Faculty of Biology, University of Belgrade, Takovska 43, 11000 Belgrade, Serbia
Vladan Bajic
Laboratory for Radiology and Molecular Genetics, Institute for Nuclear Sciences "Vinca," University of Belgrade, Belgrade, Serbia
Biljana Spremo-Potparević
Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia

SINOPSIS

Ganoderma lucidum is traditionally used in Eastern medicine to preserve vitality, promote longevity, and treat disease. It possesses immunomodulatory, antitumor, antimicrobial, and antiaging activities, among others, but one of the most important is its antioxidant property, which is the basis for other effects, because free radicals trigger many diseases. The substrate commonly used for commercial cultivation of G. lucidum is not environmentally friendly nor economically justified, so there is a need to find new alternative substrates. The aim of this study was to analyze the effect of substrate composition on the bioactivity of G. lucidum basidiocarps. G. lucidum was cultivated on 2 different substrates: (1) a mixture of wheat straw, grapevine branches, and wheat bran, and (2) wheat straw. Commercial fruiting bodies, cultivated on oak sawdust, were used as the control. 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging ability, total phenols, and flavonoid content were determined spectrophotometrically to define the antioxidative potential of basidiocarp extracts. The comet test was performed to detect the degree of DNA damage in the cells that were exposed to G. lucidum extracts before and after the effect of oxidants. Higher antioxidative potential was observed for the extract of G. lucidum basidiocarps cultivated on wheat straw compared with that from the mixed substrate and especially with commercial ones. The alternatively cultivated basidiocarps also showed stronger antigenotoxic potential compared with commercial ones. The study showed that fruiting bodies produced on wheat straw, one of the most accessible and cheapest crop residues, are more potent antioxidant and antigenotoxic agents than commercially cultivated ones.


Articles with similar content:

Selenium Enrichment of Pleurotus cornucopiae (Paulet) Rolland and Grifola frondosa (Dicks.:Fr.) S.F. Gray Mushrooms
International Journal of Medicinal Mushrooms, Vol.8, 2006, issue 1
Robert B. Beelman, Daniel J. Royse
Solid-substrate Fermentation of Wheat Grains by Mycelia of Indigenous Species of the Genus Ganoderma (Higher Basidiomycetes) to Enhance the Antioxidant Activities
International Journal of Medicinal Mushrooms, Vol.16, 2014, issue 3
Sarasvathy Subramaniam, Yee Shin Tan, Umah Rani Kuppusamy, Vikineswary Sabaratnam
Screening of Bioactive Compounds of Medicinal Mushrooms Collected on Tunisian Territory
International Journal of Medicinal Mushrooms, Vol.19, 2017, issue 2
Samira Aschi-Smiti, Ayda Khadhria, Chedia Aouadhi
Cultivation of the King-Oyster Mushroom Pleurotus eryngii (DC.:Fr.) Quél. on Substrates Deriving from the Olive-Oil Industry
International Journal of Medicinal Mushrooms, Vol.7, 2005, issue 3
Georgios I. Zervakis
Wound Healing Activity of an Aqueous Extract of the Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Higher Basidiomycetes)
International Journal of Medicinal Mushrooms, Vol.16, 2014, issue 4
Kshipra Misra, Gaurav Kr. Keshri, Prem Singh Negi, Anju Yadav, Shefali Gola, Asheesh Gupta, Vandana Kirar