Suscripción a Biblioteca: Guest
Portal Digitalde Biblioteca Digital eLibros Revistas Referencias y Libros de Ponencias Colecciones
International Journal of Medicinal Mushrooms
Factor de Impacto: 1.423 Factor de Impacto de 5 años: 1.525 SJR: 0.431 SNIP: 0.661 CiteScore™: 1.38

ISSN Imprimir: 1521-9437
ISSN En Línea: 1940-4344

Volumes:
Volumen 21, 2019 Volumen 20, 2018 Volumen 19, 2017 Volumen 18, 2016 Volumen 17, 2015 Volumen 16, 2014 Volumen 15, 2013 Volumen 14, 2012 Volumen 13, 2011 Volumen 12, 2010 Volumen 11, 2009 Volumen 10, 2008 Volumen 9, 2007 Volumen 8, 2006 Volumen 7, 2005 Volumen 6, 2004 Volumen 5, 2003 Volumen 4, 2002 Volumen 3, 2001 Volumen 2, 2000 Volumen 1, 1999

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushrooms.v17.i4.20
pages 331-338

Effects of Comb Tooth Cap Medicinal Mushroom, Hericium ramosum (Higher Basidiomycetes) Mycelia on DPPH Radical Scavenging Activity and Nerve Growth Factor Synthesis

Kohei Suruga
International Operation Department, FM Center for Research & Development, Kibun Foods Inc., Tokyo, Japan
Kazunari Kadokura
International Operation Department, FM Center for Research & Development, Kibun Foods Inc., Tokyo, Japan
Yoshihiro Sekino
International Operation Department, FM Center for Research & Development, Kibun Foods Inc., Tokyo, Japan
Takafumi Nakano
Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan
Koichi Matsuo
Department of Pharmaceutical and Health Care Management, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan
Keiichi Irie
Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan
Kenichi Mishima
Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan
Makoto Yoneyama
I.M.C Institution, Yamanashi, Japan
Yasuhiro Komatsu
Kitasato Institution for Life Science, Kitasato University, Tokyo, Japan; Sun R&D Institute for Natural Medicines Co., Inc., Tokyo, Japan

SINOPSIS

The goal of this study was to evaluate the antioxidant effects of and nerve growth factor (NGF) synthesis caused by Hericium ramosum mycelia. Wild mushroom fruiting bodies were collected from nature to isolate their mycelia. Pieces of H. ramosum fruiting bodies were plated onto 90-mm Petri dishes with potato dextrose agar medium to isolate their mycelia. Antioxidant activity was measured using 1,1-diphenyl-2-picryl-hydrazyl (DPPH) free radical scavenging activity in vitro; the ethanol extract from H. ramosum mycelia (63.11 µmol Trolox/g) was more potent than that of other mushroom mycelia extracts. There was a proportional relationship (R2 = 0.7929) between DPPH radical scavenging activity and total phenolic content in extracts of different mushroom mycelia. We investigated the ability of H. ramosum mycelia to inducing NGF synthesis in vivo. Oral administration of H. ramosum mycelia significantly increased concentrations of NGF in the hippocampus of intact mice. These results are the first concerning antioxidant activity and NGF synthesis of H. ramosum mycelia. These mushroom mycelia could be useful as food and/or nutritional supplements because of certain biological functions.


Articles with similar content:

Study of Hypsizygus marmoreus (Peck) Bigel. and Grifola frondosa (Dicks.: Fr.) S.F. Gray: Cultural-Morphological Peculiarities, Growth Characteristics, Qualitative Enzymatic Activity, and Resistance to Fungal Pest Contamination
International Journal of Medicinal Mushrooms, Vol.8, 2006, issue 4
Alexander Beharav, Eden Akavia, Eviatar D. Nevo
Correlation of Antioxidant Activity with Content of Phenolics in Extracts from the Culinary-Medicinal Abalone Mushroom Pleurotus abalones Han, Chen et Cheng (Agaricomycetideae)
International Journal of Medicinal Mushrooms, Vol.7, 2005, issue 1&2
Yun Jiang, Rong-Rong Chen, Fang Liu, Li Zhao, Le Li, Tzi Bun Ng, Ming Fu
Total Phenolic Content and Antioxidant Activity of Mycelial Extracts from the Medicinal Fungus Paecilomyces hepiali (Ascomycetes)
International Journal of Medicinal Mushrooms, Vol.19, 2017, issue 1
Yi Li, Abdessamad Imoulan, Lan Jiang, Wen-Jing Wang, Yi-Jian Yao
Antioxidant and Immunomodulating Activities of Exo-and Endopolysaccharide Fractions from Submerged Mycelia Cultures of Culinary-Medicinal Mushrooms
International Journal of Medicinal Mushrooms, Vol.15, 2013, issue 3
Karthik Marripudi, Cheang Khoo, Sundar Rao Koyyalamudi, Jong Pil Park, Jin Hee Kim, Sang-Chul Jeong, Chi-Hyun Song, J. Margaret Hughes, Trevor Bailey
Activity-Guided Fractionation and Evaluation of Potent Antioxidants from Extract of Angel Wings Mushroom, Pleurotus porrigens (Higher Basidiomycetes)
International Journal of Medicinal Mushrooms, Vol.15, 2013, issue 1
Hip Seng Yim, Fook Yee Chye, Chun Wai Ho, Chiaw Mei Sia, Loshnie Samuagam, Sook Yee Mah