RT Journal Article ID 51f0c47f5d139595 A1 Tsai, Jie-Chung A1 Lung, Ming-Yeou T1 Antioxidant Properties of Polysaccharides from the Willow Bracket Medicinal Mushroom, Phellinus igniarius (L.) Quél. (Aphyllophoromycetideae) in Submerged Culture JF International Journal of Medicinal Mushrooms JO IJM YR 2009 FD 2009-11-16 VO 11 IS 4 SP 383 OP 394 K1 Phellinus igniarius K1 medicinal mushrooms K1 intracellular polysaccharide K1 exopolysaccharide K1 antioxidant activity AB Investigated were antioxidant properties of intracellular polysaccharides (IPS) and exopolysaccharides (EPS) obtained respectively from mycelia and filtrates of submerged culture by Phellinus igniarius in a stirred-tank bioreactor. Also examined were superoxide and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging activities, chelating ability, reducing power, and antioxidant activity (AOA) by IPS and EPS. The high number average molecular weights of EPS (835 kDa) and IPS (574 kDa) were obtained, and their protein/polysaccharide ratios of IPS and EPS are equivalent (1.80%) by Ph. igniarius submerged culture. Low EC50 values below 5 mg/mL were relied upon as evidence that EPS possessed good antioxidant activity, scavenging effect on DPPH radicals, chelating effect on ferrous ions, and scavenging effect on superoxide anions, whereas IPS exhibited good reducing power, chelating effect on ferrous ions and scavenging effect on superoxide anions. The positive results of this research may lead to the development of a potential polysaccharide-related antioxidant for treating human disease. PB Begell House LK https://www.dl.begellhouse.com/journals/708ae68d64b17c52,4554be083929b23c,51f0c47f5d139595.html