RT Journal Article
ID 736f002a687dc8bd
A1 Liu, Yong 
A1 Ma, Chaoyu 
A1 Zhang, Nu
T1 Tissue-Specific Control of Tissue-Resident Memory T Cells
JF Critical Reviews™ in Immunology
JO CRI
YR 2018
FD 2018-04-26
VO 38
IS 2
SP 79
OP 103
K1 CD4
K1 CD8
K1 infection
K1 IL-15
K1 Memory
K1 TGF-beta
AB Tissue-resident memory T (T<sub>RM</sub>) cells have emerged as a major component of T cell biology. Recent investigations have greatly advanced our understanding of T<sub>RM</sub>s. Common features have been discovered to distinguish memory T cells residing in various mucosal and non-mucosal tissues from their circulating counterparts. Given that most organs and tissues contain a unique microenvironment, local signal-induced tissue-specific features are tightly associated with the differentiation, homeostasis, and protective functions of T<sub>RM</sub>s. Here, we discuss recent advances in the T<sub>RM</sub> field with a special emphasis on the interaction between local signals and T<sub>RM</sub>s in the context of individual tissue environment.


PB Begell House
LK https://www.dl.begellhouse.com/journals/2ff21abf44b19838,443ae0ff4b5271d1,736f002a687dc8bd.html