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Journal of Environmental Pathology, Toxicology and Oncology

Publication de 4  numéros par an

ISSN Imprimer: 0731-8898

ISSN En ligne: 2162-6537

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 2.4 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.8 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.5 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00049 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.59 SJR: 0.429 SNIP: 0.507 CiteScore™:: 3.9 H-Index: 49

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Naringenin Alleviates Cadmium-Induced Toxicity through the Abrogation of Oxidative Stress in Swiss Albino Mice

Volume 35, Numéro 2, 2016, pp. 161-169
DOI: 10.1615/JEnvironPatholToxicolOncol.2016015892
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RÉSUMÉ

The present study evaluates the protective potential of the flavonoid naringenin (NRG) against experimentally induced cadmium (Cd) toxicity in Swiss albino mice. NRG (4 and 8 mg/kg) was orally administered to mice 30 min before oral administration of CdCl2 (12 mg/kg) for 11 consecutive days. On the 12th day, we evaluated body and organ weights, hematological profiles, serum biochemical profiles, and hepatic and renal tissue antioxidative parameters including lipid peroxidation, reduced and oxidized glutathione, glutathione-S-transferase, glutathione peroxidase, glutathione reductase, superoxide dismutase, and catalase. Cotreatment with NRG markedly and significantly normalized body and organ weights, hematological profiles, and serum biochemical profiles and significantly modulated all of the hepatic and renal tissue biochemical parameters in Cd-intoxicated mice. The present findings show that NRG possesses a remarkable alleviative effect against Cd-induced toxicity in albino mice, mediated by abrogation of Cd-induced oxidative stress by multiple mechanisms.

CITÉ PAR
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  2. Bhattacharya Sanjib, The role of medicinal plants and natural products in melioration of cadmium toxicity, Oriental Pharmacy and Experimental Medicine, 18, 3, 2018. Crossref

  3. Hernández-Aquino Erika, Muriel Pablo, Beneficial effects of naringenin in liver diseases: Molecular mechanisms, World Journal of Gastroenterology, 24, 16, 2018. Crossref

  4. Athmouni Khaled, Belhaj Dalel, Chawech Rachid, Jarraya Raoudha, El Feki Abdelfattah, Ayadi Habib, Characterization of polysaccharides isolated from Periploca angustifolia and its antioxidant activity and renoprotective potential against cadmium induced toxicity in HEK293 cells and rat kidney, International Journal of Biological Macromolecules, 125, 2019. Crossref

  5. Karim Naymul, Jia Zhenquan, Zheng Xiaodong, Cui Sunliang, Chen Wei, A recent review of citrus flavanone naringenin on metabolic diseases and its potential sources for high yield-production, Trends in Food Science & Technology, 79, 2018. Crossref

  6. Jin Yuzi, Wang Hua, Naringenin Inhibit the Hydrogen Peroxide-Induced SH-SY5Y Cells Injury Through Nrf2/HO-1 Pathway, Neurotoxicity Research, 36, 4, 2019. Crossref

  7. El-Saad Ahmed Mokhtar Abu, Abdel-Waha Wessam Mohamad, Naringenin Attenuates Toxicity and Oxidative Stress Induced by Lambda-cyhalothrin in Liver of Male Rats, Pakistan Journal of Biological Sciences, 23, 4, 2020. Crossref

  8. Bhattacharya Sanjib, The Role of Probiotics in the Amelioration of Cadmium Toxicity, Biological Trace Element Research, 197, 2, 2020. Crossref

  9. Chen Cong, Jie Xu, Ou Yangjie, Cao Yini, Xu Lu, Wang Yunxia, Qi Rong, Nanoliposome improves inhibitory effects of naringenin on nonalcoholic fatty liver disease in mice, Nanomedicine, 12, 15, 2017. Crossref

  10. Yang Yuanying, Wei Shanshan, Zhang Bikui, Li Wenqun, Recent Progress in Environmental Toxins-Induced Cardiotoxicity and Protective Potential of Natural Products, Frontiers in Pharmacology, 12, 2021. Crossref

  11. Naraki Karim, Rezaee Ramin, Karimi Gholamreza, A review on the protective effects of naringenin against natural and chemical toxic agents, Phytotherapy Research, 35, 8, 2021. Crossref

  12. Rajasekar Mani, Adverse effect of synthesized Naringenin derivatives investigate with Zebrafish (Danio rerio) embryos, Results in Chemistry, 2, 2020. Crossref

  13. Picos-Salas Manuel Adrian, Cabanillas-Bojórquez Luis Ángel, Elizalde-Romero Cristina Alicia, Leyva-López Nayely, Montoya-Inzunza Luis Aurelio, Heredia J. Basilio, Gutiérrez-Grijalva Erick P., Naringenin as a Natural Agent Against Oxidative Stress and Inflammation, and Its Bioavailability, Food Reviews International, 2022. Crossref

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