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Journal of Environmental Pathology, Toxicology and Oncology

Publication de 4  numéros par an

ISSN Imprimer: 0731-8898

ISSN En ligne: 2162-6537

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 2.4 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.8 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.5 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00049 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.59 SJR: 0.429 SNIP: 0.507 CiteScore™:: 3.9 H-Index: 49

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Trichosanthes dioica Fruit Extract Ameliorates Arsenic-Induced Brain Toxicity in Male Albino Rats

Volume 32, Numéro 2, 2013, pp. 141-148
DOI: 10.1615/JEnvironPatholToxicolOncol.2013007557
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RÉSUMÉ

This study evaluated the ameliorative potential of aqueous extract of Trichosanthes dioica fruit (AQTD) against arsenic-induced toxicity in rat brain. AQTD (50 and 100 mg/kg) was administered orally to male Wistar albino rats for 20 consecutive days before oral administration of sodium arsenite (10 mg/kg) for 8 days. We then evaluated the brain biochemical parameters viz. lipid peroxidation, reduced and oxidized glutathione, glutathione-S-transferase, glutathione peroxidase, glutathione reductase, superoxide dismutase, catalase, and DNA fragmentation. Pretreatment with AQTD significantly and dose dependently modulated all the antioxidative parameters and reduced DNA fragmentation in rat brain intoxicated with arsenic. These findings conclude that T. dioica fruit possesses a remarkable ameliorative effect against arsenic-induced brain toxicity in male albino rats, which is mediated by alleviation of arsenic-induced oxidative stress by multiple mechanisms.

CITÉ PAR
  1. An Yuan, Liu Tingting, Liu Xiaona, Zhao Lijun, Wang Jing, Rac1 and Cdc42 Play Important Roles in Arsenic Neurotoxicity in Primary Cultured Rat Cerebellar Astrocytes, Biological Trace Element Research, 170, 1, 2016. Crossref

  2. Khandaker Mahia, Akter Saleha, Imam Mohammad Zafar, Trichosanthes dioica Roxb.: A vegetable with diverse pharmacological properties, Food Science and Human Wellness, 7, 1, 2018. Crossref

  3. Goldar Waquar Ahmed, Jana Sandipan, Kumari Reshma, Bhattacharya Sanjib, Haldar Pallab Kanti, Litsea cubeba fruit attenuates diabetes-associated metabolic complications in mice, Bulletin of the National Research Centre, 46, 1, 2022. Crossref

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