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Journal of Environmental Pathology, Toxicology and Oncology

Publication de 4  numéros par an

ISSN Imprimer: 0731-8898

ISSN En ligne: 2162-6537

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 2.4 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.8 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.5 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00049 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.59 SJR: 0.429 SNIP: 0.507 CiteScore™:: 3.9 H-Index: 49

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Radioprotective Role of Selenium after Single-Dose Radioiodine (131I) Exposure to Red Blood Cells of Rats

Volume 30, Numéro 2, 2011, pp. 153-162
DOI: 10.1615/JEnvironPatholToxicolOncol.v30.i2.60
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RÉSUMÉ

The present study elucidated the protective potential of selenium following 131I-induced alterations in rat blood. Forty rats were segregated into 4 groups. Animals in Group I served as normal controls, Group II animals were injected with a single dose of 3.7 Mbq of 131I (carrier free), Group III animals were supplemented with selenium (1 ppm), and Group IV animals were given a combined treatment of selenium and 131I. 131I treatment of rats showed significant increases in total leukocyte counts (TLCs), lymphocytes, and neutrophils (monocytes and eosinophils were not recorded). These were significantly restored upon supplementation of selenium. Lipid peroxidase (LPO), glutathione peroxidase (GSH-PX), reduced glutathione (GSH), superoxide dismutase (SOD), and δ-aminolevulinic acid dehydratase (δ-ALAD) were found to be enhanced following 131I treatment. However, the levels of catalase were found to be decreased. Selenium administration to 131I-treated rats resulted in significant restoration of these enzyme activities. Scanning electron microscope (SEM) studies also revealed various surface deformities in erythrocytes after 131I treatment, which upon supplementation with selenium were significantly restored. In conclusion, selenium may prove to be an effective radioprotector following 131I treatment.

CITÉ PAR
  1. Sochor Jiri, Pohanka Miroslav, Ruttkay-Nedecky Branislav, Zitka Ondrej, Hynek David, Mares Petr, Zeman Ladislav, Adam Vojtech, Kizek Rene, Effect of selenium in organic and inorganic form on liver, kidney, brain and muscle of Wistar rats, Open Chemistry, 10, 5, 2012. Crossref

  2. Hazbavi Maryam, Zarei Mansoureh, Nazaralivand Roghayeh, Shahbazian Hojattollah, Cheki Mohsen, Protection from ionizing radiation-induced genotoxicity and apoptosis in rat bone marrow cells by HESA-A: a new herbal-marine compound, Journal of Bioenergetics and Biomembranes, 51, 5, 2019. Crossref

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