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Nanoscience and Technology: An International Journal

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ISSN Imprimer: 2572-4258

ISSN En ligne: 2572-4266

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.3 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.7 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.7 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00023 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.11 SJR: 0.244 SNIP: 0.521 CiteScore™:: 3.6 H-Index: 14

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DIFFUSION MODEL OF DRUG NANOPORE FILLING

Volume 11, Numéro 4, 2020, pp. 327-341
DOI: 10.1615/NanoSciTechnolIntJ.2020035786
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RÉSUMÉ

Processes in porous media are important for various applications, including biophysics and medicine. The characteristic features of the processes on macro- and mesoscale levels are connected with the fact that the transfer processes in small pores are influenced by physical phenomena which are insignificant for ordinary materials. In this paper, a diffusion model for filling small pores with a drug is proposed, taking into account the dependence of the diffusion coefficient on the coordinate. As a result of numerical study, differences in the distributions of concentration for different variants of such dependence have been established. It was shown that the type of the isotherm (Henry's, Freundlich's, and Langmuir's) can lead to quantitative changes in the concentration distributions in the pore, but no qualitative changes were found. It is shown that for any variant there is a deceleration in the process of pore filling with the drug, and there is an incomplete filling due to both adsorption and diffusion. As the pore size decreases, the limiting pore filling also decreases.

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