Abonnement à la biblothèque: Guest
Portail numérique Bibliothèque numérique eBooks Revues Références et comptes rendus Collections
Forum on Immunopathological Diseases and Therapeutics
SJR: 0.309 SNIP: 0.041 CiteScore™: 0.18

ISSN Imprimer: 2151-8017
ISSN En ligne: 2151-8025

Archives: Volume 1, 2010 to Volume 7, 2016

Forum on Immunopathological Diseases and Therapeutics

DOI: 10.1615/ForumImmunDisTher.2017019621
pages 213-224

Immune Complex Analysis in Active Lyme Disease

Steven E. Schutzer
Rutgers New Jersey Medical School, Newark, NJ 07103
P. K. Coyle
Stony Brook University Department of Neurology, Stony Brook, NY 11794

RÉSUMÉ

Lyme disease (LD) is a growing infectious disease. Assays that can detect active infection early are needed to allow appropriate antibiotic therapy to begin when there is the best chance for a cure. The most frequently used assays are those based on antibodies to Borrelia burgdorferi or its variants, the causative agent of LD. However, an antibody test at a single time point only measures exposure, not necessarily an active infection. In contrast, antibodies that are bound to a target antigen in a circulating immune complex form do indicate active infection. Here, we present data supporting the use of such assays in LD.


Articles with similar content:

A Brief Chronicle of CD4 as a Biomarker for HIV/AIDS: A Tribute to the Memory of John L. Fahey
Forum on Immunopathological Diseases and Therapeutics, Vol.6, 2015, issue 1-2
Ana M. Sanchez, Alan Landay, Thomas N. Denny, Jonathan M. Kagan
Quantitating Therapeutically Relevant T-Cell Responses to Cancer Vaccines
Critical Reviews™ in Immunology, Vol.21, 2001, issue 1-3
H. Kim Lyerly, Michael A. Morse, Timothy M. Clay, Paul J. Mosca, Amy C. Hobeika
Laparoscopic Approach to Pancreatic Disease
Journal of Long-Term Effects of Medical Implants, Vol.14, 2004, issue 1
Adrian Park, Gina L. Adrales
Current Vaccination Strategies for the Treatment of B-Cell Lymphoma and Multiple Myeloma
Critical Reviews™ in Immunology, Vol.29, 2009, issue 5
Nurit Hollander
Microenvironmental Hypoxia Orchestrating the Cell Stroma Cross Talk, Tumor Progression and Antitumor Response
Critical Reviews™ in Immunology, Vol.31, 2011, issue 5
Muhammad Zaeem Noman, Yosra Messai, Thibault Carre, Salem Chouaib, Bassam Janji, Meriem Hasmim, Intissar Akalay, Marine Meron