Publication de 6 numéros par an
ISSN Imprimer: 0743-4863
ISSN En ligne: 2162-660X
Indexed in
The Use and Development of Retroviral Vectors to Deliver Cytokine Genes for Cancer Therapy
RÉSUMÉ
In this review, we describe technical advancements of retroviral vectors to address issues of safety, liter, and clinical scale manufacturing to produce high-quality retroviral vector preparations that have made direct intratumoral administration of cytokine encoding recombinant vectors a feasible cancer therapy in the clinic. We also review possible further advances in retroviral vector design, which may prove important in expanding these clinical applications.
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Lundqvist Andreas, Noffz Gabriele, Pavlenko Maxim, Sæbøe-Larssen Stein, Fong Timothy, Maitland Norman, Pisa Pavel, Nonviral and Viral Gene Transfer Into Different Subsets of Human Dendritic Cells Yield Comparable Efficiency of Transfection, Journal of Immunotherapy, 25, 6, 2002. Crossref
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