Abonnement à la biblothèque: Guest
Portail numérique Bibliothèque numérique eBooks Revues Références et comptes rendus Collections
Critical Reviews™ in Biomedical Engineering
SJR: 0.207 SNIP: 0.376 CiteScore™: 0.79

ISSN Imprimer: 0278-940X
ISSN En ligne: 1943-619X

Volumes:
Volume 47, 2019 Volume 46, 2018 Volume 45, 2017 Volume 44, 2016 Volume 43, 2015 Volume 42, 2014 Volume 41, 2013 Volume 40, 2012 Volume 39, 2011 Volume 38, 2010 Volume 37, 2009 Volume 36, 2008 Volume 35, 2007 Volume 34, 2006 Volume 33, 2005 Volume 32, 2004 Volume 31, 2003 Volume 30, 2002 Volume 29, 2001 Volume 28, 2000 Volume 27, 1999 Volume 26, 1998 Volume 25, 1997 Volume 24, 1996 Volume 23, 1995

Critical Reviews™ in Biomedical Engineering

DOI: 10.1615/CritRevBiomedEng.v39.i4.60
pages 337-359

Oscillation Mechanics of the Respiratory System: Applications to Lung Disease

David W. Kaczka
Beth Israel Deaconess Medical Center
Raffaele L. Dellaca
Dipartimento di Bioingegneria, Politecnico di Milano University, Milano, Italy

RÉSUMÉ

Since its introduction in the 1950s, the forced oscillation technique (FOT) and the measurement of respiratory impedance have evolved into powerful tools for the assessment of various mechanical phenomena in the mammalian lung during health and disease. In this review, we highlight the most recent developments in instrumentation, signal processing, and modeling relevant to FOT measurements. We demonstrate how FOT provides unparalleled information on the mechanical status of the respiratory system compared to more widely used pulmonary function tests. The concept of mechanical impedance is reviewed, as well as the various measurement techniques used to acquire such data. Emphasis is placed on the analysis of lower, physiologic frequency ranges (typically less than 10 Hz) that are most sensitive to normal physical processes as well as pathologic structural alterations. Various inverse modeling approaches used to interpret alterations in impedance are also discussed, specifically in the context of three common respiratory diseases: asthma, chronic obstructive pulmonary disease, and acute lung injury. Finally, we speculate on the potential role for FOT in the clinical arena.


Articles with similar content:

Air Pollution's Effects on the Human Respiratory System
Critical Reviews™ in Biomedical Engineering, Vol.44, 2016, issue 5
Adrian R. M. Upton, Markad V. Kamath, Nehaarika Kantipudi, Graham Jones, Vivek Patel
Model-based Approaches to Biomarker Discovery and Evaluation: A Multidisciplinary Integrated Review
Critical Reviews™ in Biomedical Engineering, Vol.30, 2002, issue 4-6
David M. Foster, Marc R. Gastonguay, Paolo Vicini
Oscillatory Mechanics in Asthma: Emphasis on Airway Variability and Heterogeneity
Critical Reviews™ in Biomedical Engineering, Vol.43, 2015, issue 2-3
Swati A. Bhatawadekar, Paul Hernandez, Geoffrey N. Maksym
Facilitating Earlier Diagnosis of Cardiovascular Disease through Point-of-Care Biosensors: A Review
Critical Reviews™ in Biomedical Engineering, Vol.46, 2018, issue 1
David Probst, Mackenzie M. Honikel, Jeffrey T. La Belle, Chi-En Lin
Lung and Heart Sounds Analysis: State-of-the-Art and Future Trends
Critical Reviews™ in Biomedical Engineering, Vol.46, 2018, issue 1
Ana L. Padilla-Ortiz, David Ibarra