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Journal of Flow Visualization and Image Processing
SJR: 0.161 SNIP: 0.312 CiteScore™: 0.5

ISSN Imprimer: 1065-3090
ISSN En ligne: 1940-4336

Journal of Flow Visualization and Image Processing

DOI: 10.1615/JFlowVisImageProc.v16.i2.30
pages 137-158


John M. Furlan
Case Western Reserve University
Jaikrishnan R. Kadambi
Department of Mechanical Engineering, Case Western Reserve University, Cleveland, Ohio, U.S.A.
Kenneth A. Loparo
Department of Electrical Engineering and Computer Science, Case Western Reserve University, Cleveland, OH
Sree N. Sreenath
Department of Electrical Engineering and Computer Science, Case Western Reserve University, Cleveland, OH
Sunil Manjila
School of Medicine, Case Western Reserve University, Cleveland, OH


In order to characterize the flow of Cerebral Spinal Fluid (CSF) within the third ventricle and cerebral aqueduct of a healthy adult, an in vitro steady flow loop is developed. Rapid Prototyping (RP) technology is used to create a geometrically realistic ventricular model. Particle Image Velocimetry (PIV) is used to obtain 2D velocity vector maps of the flow in the mid-sagittal plane of the model for the cranio-caudal as well as caudo-cranial flow directions. CSF steady flow rates used correspond to the physiological flow rate range. The PIV results demonstrate that the highest velocities occur in the mid-aqueduct region of the test section and the lowest velocities occur in a dead zone located in the antero-inferior region of the third ventricle. In the case of cranio-caudal flow, the results show a relatively small recirculation region located adjacent to a downward jet resulting from the influx of CSF from the Foramen of Monro. The results of this study have implications with respect to pathophysiology of hydrocephalus, mechanisms of CSF diversion in shunt surgery and Endoscopic Third Ventriculostomy (ETV), targeted drug delivery via CSF, and verification of CFD models of CSF flow.

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