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Critical Reviews™ in Eukaryotic Gene Expression

Publication de 6  numéros par an

ISSN Imprimer: 1045-4403

ISSN En ligne: 2162-6502

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

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Molecular Docking Studies of Potential Inhibition of the Alcohol Dehydrogenase Enzyme by Phyllanthin, Hypophyllanthin and Gallic Acid

Volume 29, Numéro 4, 2019, pp. 287-294
DOI: 10.1615/CritRevEukaryotGeneExpr.2019025602
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RÉSUMÉ

A review of literature shows certain phytochemicals, phyllanthin, hypophyllanthin and gallic acid have beneficial effects in experimental animals for improving liver metabolism in alcoholic liver disease. We investigated the ability of these chemicals to exhibit the inhibitory effect on the enzyme, alcohol dehydrogenase active site. The software used were CASTp, AutoDock and Molinspiration in Windows platform. We observed the phytochemicals, phyllanthin (−2.37 kcal/mol), hypophyllanthin (−3.23 kcal/mol) and gallic acid (−5.85 kcal/mol) in the order of increasing binding efficiency, which was as good as 4-methyl pyrazole (−4.18 kcal/mol).

RÉFÉRENCES
  1. Han K-H, Hashimoto N, Fukushima M. Relationships among alcoholic liver disease, antioxidants, and antioxidant enzymes. World J Gastroenterol. 2016;22:37-49.

  2. Chen X. Protective effects of quercetin on liver injury induced by ethanol. Pharmacogn Mag. 2010;6:135-141.

  3. Shankari SG, Karthikesan K, Jalaludeen AM, Ashokkumar N. Hepatoprotective effect of morin on ethanol-induced hepatotoxicity in rats. J Basic Clin Physiol Pharmacol. 2010;21:277-294.

  4. Li D, Ren D, Luo Y, Yang X. Protective effects of ursolic acid against hepatotoxicity and endothelial dysfunction in mice with chronic high choline diet consumption. Chem Biol Interact. 2016;258:102-107.

  5. Yao P, Li K, Song F, Zhou S, Sun X, Zhang X, Nussler AK, Liu, L. Heme oxygenase-1 upregulated by Ginkgo biloba extract: potential protection against ethanol-induced oxidative liver damage. Food Chem. Toxicol Int J Publ Br Ind Biol Res Assoc. 2007;45:1333-1342.

  6. Hanh ND, Sinchaipanid N, Mitrevej A. Physicochemical characterization of phyllanthin from Phyllanthus amarus Schum et Thonn. Drug Dev Ind Pharm. 2014;40:793- 802.

  7. Tripathi AK, Verma RK, Gupta AK, Gupta MM, Khanuja SPS. Quantitative determination of phyllanthin and hypophyllanthin in Phyllanthus species by high-performance thin layer chromatography. Phytochem Anal PCA. 2006;17:394-397.

  8. Olayinka ET, Ore A, Ola OS, Adeyemo OA. Ameliorative effect of gallic acid on cyclophosphamide-induced oxidative injury and hepatic dysfunction in rats. Med Sci (Basel). 2015;3:78-92.

  9. McMartin KE, Collins TD. Distribution of oral 4-methylpyrazole in the rat: inhibition of elimination by ethanol. J Toxicol Clin Toxicol. 1988;26:451-66.

  10. Lee S-L, Lee Y-P, Wu M-L, Chi Y-C, Liu C-M, Lai C-L, Yin S-J. Inhibition of human alcohol and aldehyde dehydrogenases by aspirin and salicylate: assessment of the effects on first-pass metabolism of ethanol. Biochem Pharmacol. 2015;95:71-79.

  11. Haseba T, Sugimoto J, Sato S, Abe Y, Ohno Y. Phytophenols in whisky lower blood acetaldehyde level by depressing alcohol metabolism through inhibition of alcohol dehydrogenase 1 (class I) in mice. Metabolism. 2008;57:1753-1759.

  12. Kartkaya K, Oglakfi A, Senturk H, Bayramoglu G, Canbek M, Kanbak G. Investigation of the possible protective role of gallic acid on paraoxanase and arylesterase activities in livers of rats with acute alcohol intoxication. Cell Biochem Funct. 2013;31(3):208-13.

  13. Blomstrand R, Lof A, Ostling H. Studies on the metabolic effects of long-term administration of ethanol and 4-methylpyrazole in the rat. Vitamin A depletion in the liver. Nutr Metab. 1977;21(Suppl 1):148-151.

  14. Hurley TD, Bosron WF, Stone CL, Amzel LM. Structures of three human beta alcohol dehydrogenase variants. Correlations with their functional differences. J Mol Biol. 1994;239:415-429.

  15. Chirdchupunseree H, Pramyothin P. Protective activity of phyllanthin in ethanol-treated primary culture of rat hepatocytes. J Ethnopharmacol. 2010;128:172-176.

  16. Takahashi T, Sugawara W, Takiguchi Y, Takizawa K, Nakabayashi A, Nakamura M, Nagano-Ito M, Ichikawa S. Identification of plants that inhibit lipid droplet formation in liver cells: Rubus suavissimus leaf extract protects mice from high-fat diet-induced fatty liver by directly affecting liver cells. Evid-Based Comp Altern Med. 2016:4282758.

CITÉ PAR
  1. Naik Janhavi, Kulkarni Duttraj, Kadu Pramod, Pandya Aditya, Kale Pravin, Use of In silico tools for screening buffers to overcome physical instability of Abatacept, Transplant Immunology, 71, 2022. Crossref

  2. Huang Xiaojian, Zhang Siyao, Li Yushan, Yang Xi, Li Na, Zeng Guofang, Chen Fengping, Tuo Xun, Insight into the binding characteristics of rutin and alcohol dehydrogenase: Based on the biochemical method, spectroscopic experimental and molecular model, Journal of Photochemistry and Photobiology B: Biology, 228, 2022. Crossref

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